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CBFB 蛋白

(Core-Binding Factor, beta Subunit (CBFB))

The protein encoded by this gene is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit\; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters. Alternative splicing generates two mRNA variants, each encoding a distinct carboxyl terminus. In some cases, a pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript consisting of the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain 11. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

recommended

CBFB Protein (AA 74-163) (GST tag) (ABIN1348166)

CBFB 宿主: 人宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

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recommended

CBFB Protein (AA 1-182) (GST tag) (ABIN1348164)

CBFB 宿主: 人宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

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recommended

CBFB Protein (AA 1-182) (His tag) (ABIN7417792)

CBFB 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS, WB, Imm, PC

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CBFB 蛋白 by Origin

Find CBFB 蛋白 for a variety of species such as anti-Human CBFB, anti-Mouse CBFB. The species listed below are among those available. Click on a link to go to the corresponding products.

CBFB 蛋白 by Source

Here you will find CBFB 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

CBFB 蛋白 by 蛋白类型

Here you can find CBFB 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

CBFB 蛋白 by 应用范围

Find CBFB 蛋白 validated for a specific application such as WB, SDS, ELISA, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular CBFB 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

CBFB Protein (AA 74-163) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1348166

Quantity 10 μg

Datasheet Datasheet

CBFB Protein (AA 1-182) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1348164

Quantity 10 μg

Datasheet Datasheet

CBFB Protein (AA 1-182) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7417792

Quantity 100 μg

Datasheet Datasheet

CBFB Protein (AA 1-187) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7418203

Quantity 100 μg

Datasheet Datasheet

CBFB 蛋白

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN2128359

Quantity 50 μg

Datasheet Datasheet

CBFB Protein (AA 1-182) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3085782

Quantity 1 mg

Datasheet Datasheet

CBFB Protein (AA 1-187) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3121502

Quantity 1 mg

Datasheet Datasheet

CBFB Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2713253

Quantity 20 μg

Datasheet Datasheet

Aliases for CBFB 蛋白

core-binding factor beta subunit (CBFB) 蛋白
core binding factor beta subunit (Cbfb) 蛋白
core-binding factor, beta subunit (cbfb) 蛋白
core-binding factor, beta subunit (Cbfb) 蛋白
core-binding factor, beta subunit S homeolog (cbfb.S) 蛋白
core binding factor beta (Cbfb) 蛋白
core-binding factor beta subunit (Cbfb) 蛋白
AI893578 蛋白
cbf-beta 蛋白
Cbfb 蛋白
CBFB 蛋白
cbfbeta 蛋白
PEA2 蛋白
pea2-beta 蛋白
Pebp2 蛋白
pebp2-beta 蛋白
PEBP2B 蛋白
pebp2b 蛋白
PEBP2b 蛋白
Pebpb2 蛋白
unp1266 蛋白

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CBFB 蛋白 by Origin

CBFB 蛋白 by Source

CBFB 蛋白 by 蛋白类型

CBFB 蛋白 by 应用范围

Popular CBFB 蛋白

Aliases for CBFB 蛋白

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