Cancer Immune Checkpoints
Inhibitory T-Cell Receptors
TIM 3 - TIM3:
LAG3 (Lymphocyte-Activation Gene 3):
VISTA (V-type immunoglobulin domain-containing suppressor of T-cell activation):
TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains):
BTLA (B and T Lymphocyte Associated):
TNFRSF14 - HVEM:
KIR2DL3 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3):
TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4):
TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14):
Major Histocompatibility Complex
HLA-A (Major Histocompatibility Complex, Class I, A):
MR1 (Major Histocompatibility Complex, Class I-Related):
HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G):
HLA-B (Major Histocompatibility Complex, Class I, B):
HLA-ABC (HLA-ABC):
HLA-DMA (Major Histocompatibility Complex, Class II, DM alpha):
HLA-DMB (Major Histocompatibility Complex, Class II, DM beta):
HLA-DOB (Major Histocompatibility Complex, Class II, DO beta):
HLA-DPA1 (Major Histocompatibility Complex, Class II, DP alpha 1):
HLA-DPB1 (Major Histocompatibility Complex, Class II, DP beta 1):
HLA-DQA1 (Major Histocompatibility Complex, Class II, DQ alpha 1):
HLA-DQB1 (Major Histocompatibility Complex, Class II, DQ beta 1):
HLA-DRB1 (Major Histocompatibility Complex, Class II, DR beta 1):
HLA-DRB3 (Major Histocompatibility Complex, Class II, DR beta 3):
HLA-DRB5 (Major Histocompatibility Complex, Class II, DR beta 5):
CD74 (HLA-DR-gamma):
Stimulatory T-Cell Receptors
CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4):
PD-L1 (CD274):
TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4):
ADORA2A - Adenosine A2a Receptor:
ACVR2B (Activin A Receptor, Type IIB):
CD226 (CD226):
CD27 (CD27 Molecule):
CD276 (CD276):
CD40LG - CD40 Ligand:
CD40 (CD40):
CD70 (CD70 Molecule):
CD80 (CD80):
ICOS (Inducible T-Cell Co-Stimulator):
PVR - Poliovirus Receptor:
PDCD1 - PD-1:
TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9):
TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18):
TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4):
TNFRSF9 - CD137:
Cytokine
IL1A (Interleukin 1 alpha):
IL1B - IL-1 beta:
IL1F6 - IL36A/IL1F6:
IL1RN (Interleukin 1 Receptor Antagonist):
IL10 - IL-10:
IL12 (Interleukin 12):
IL18 - IL-18:
IL6 - IL-6:
IL6RA (Interleukin 6 Receptor, alpha):
IL6ST - CD130/gp130:
IL6R - IL-6 Receptor:
TGFB1 (Transforming Growth Factor, beta 1):
IL1R1 (Interleukin 1 Receptor, Type I):
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