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Myc Proto-Oncogene protein 产品

(Myc Proto-Oncogene protein (MYC))

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The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008].

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Featured Myc Proto-Oncogene protein Categories

Myc Proto-Oncogene protein 抗体

High quality antibodies with extensive validation data.

Myc Proto-Oncogene protein ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Myc Proto-Oncogene protein 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Myc Proto-Oncogene protein 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (1)
  • (6)
Cat. No. ABIN561891
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF, IP, ICC, ChIP
Validations
  • (5)
  • (8)
Cat. No. ABIN2855631
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (7)
Cat. No. ABIN7265076
Quantity 200 μL
Datasheet Datasheet

Recommended Myc Proto-Oncogene protein ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968711
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968710
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968709
Quantity 96 tests
Datasheet Datasheet

Recommended Myc Proto-Oncogene protein 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (2)
  • (1)
Cat. No. ABIN1311716
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1311718
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (14)
  • (1)
Cat. No. ABIN2715370
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our Myc Proto-Oncogene protein Products

El-Rasikh, Farghali, Abdelrahman, Elgaffary, Abdelmalek, Emam, Ghoneim, Selim: "The implication of autoantibodies in early diagnosis and monitoring of plasmonic photothermal therapy in the treatment of feline mammary carcinoma." in: Scientific reports, Vol. 11, Issue 1, pp. 10441, (2021) (PubMed).

Zhang, Nie, Zhou, Hu, Duan, Gu, Jiang, Wang, Deng, Chen, Chen, Wang: "Oxidative stress-induced mitophagy is suppressed by the miR-106b-93-25 cluster in a protective manner." in: Cell death & disease, Vol. 12, Issue 2, pp. 209, (2021) (PubMed).

Li, Zhang, Wang, Lin, Cheng, Wang, Wang: "Long non-coding RNA CTSLP8 mediates ovarian cancer progression and chemotherapy resistance by modulating cellular glycolysis and regulating c-Myc expression through PKM2." in: Cell biology and toxicology, (2021) (PubMed).

Qi, Yang, Si, Nie: "Wnt/β‑catenin signaling modulates piperine‑mediated antitumor effects on human osteosarcoma cells." in: Molecular medicine reports, Vol. 21, Issue 5, pp. 2202-2208, (2021) (PubMed).

Liu, Zhang, Yang, Liu, Yang, Shi, Jiang, Qin: "Manipulating ZmEXPA4 expression ameliorates the drought-induced prolonged anthesis and silking interval in maize." in: The Plant cell, Vol. 33, Issue 6, pp. 2058-2071, (2021) (PubMed).

Chen, Ding, Chen, Hu, Lu, Wu, Zhang, Yang, Wu, Peng, Xie, Zhou, Wu, Zheng: "ACSL4 promotes hepatocellular carcinoma progression via c-Myc stability mediated by ERK/FBW7/c-Myc axis." in: Oncogenesis, Vol. 9, Issue 4, pp. 42, (2020) (PubMed).

Seira, Yamagata, Fukushima, Araki, Kurata, Yanagisawa, Mashimo, Nakamura, Regan, Murayama, Fujino: "Cellular density-dependent increases in HIF-1α compete with c-Myc to down-regulate human EP4 receptor promoter activity through Sp-1-binding region." in: Pharmacology research & perspectives, Vol. 6, Issue 6, pp. e00441, (2019) (PubMed).

Tang, Peng, Huang, Xie, Chen, Shen, Gao, You, Xie, Chen: "Neoisoliquiritigenin Inhibits Tumor Progression by Targeting GRP78-β- catenin Signaling in Breast Cancer." in: Current cancer drug targets, Vol. 18, Issue 4, pp. 390-399, (2018) (PubMed).

Luo, Pan, Liu, Yuan, Yan: "Sphingomyelin synthase 2 overexpression promotes cisplatin-induced apoptosis of HepG2 cells." in: Oncology letters, Vol. 15, Issue 1, pp. 483-488, (2018) (PubMed).

Li, Liu, Zhang, Cui, Ge, Wang, Chen: "Upregulation of E‑cadherin expression mediated by a novel dsRNA suppresses the growth and metastasis of bladder cancer cells by inhibiting β-catenin/TCF target genes." in: International journal of oncology, Vol. 52, Issue 6, pp. 1815-1826, (2018) (PubMed).

Synonyms and alternative names related to Myc Proto-Oncogene protein

MYC proto-oncogene, bHLH transcription factor (MYC), v-myc myelocytomatosis viral oncogene homolog (LOC100136746), nucleolar protein 3 (apoptosis repressor with CARD domain) (Nol3), MYC proto-oncogene, bHLH transcription factor (Myc), myelocytomatosis oncogene (Myc), MYC proto-oncogene, bHLH transcription factor a (myca), MYC proto-oncogene, bHLH transcription factor L homeolog (myc.L), MYC proto-oncogene, bHLH transcription factor S homeolog (myc.S), v-myc myelocytomatosis viral oncogene homolog (avian) (MYC), MYC proto-oncogene, bHLH transcription factor b (mycb), CG10798 gene product from transcript CG10798-RB (Myc), anon-WO03040301.171, ARC, AU016757, B430311C09Rik, bHLHe39, bHLHe57, c-Myc, c-myc, C-MYC, c-MYC, c-myc II, CG10798, CMYC, cmyc, CMyc, D-Myc, d-myc, da, DM, Dm, dm, dm/dMyc, dm/myc, Dmel\CG10798, DMYc, Dmyc, dMYC, dMyc, dmyc, dMyc1, dmyc1, EG:BACN5I9.1, l(1)G0139, l(1)G0354, l(1)G0359, LOC100136746, mMyc, MRTL, MYC, myc, myc-B, myc1, Myc2, myc2, MYCC, Niard, Nird, NOP, Nop30, RNCMYC, zc-myc, zgc:55680

Protein level used designations for Myc Proto-Oncogene protein

  • avian myelocytomatosis viral oncogene homolog
  • class E basic helix-loop-helix protein 39
  • myc proto-oncogene protein
  • myc-related translation/localization regulatory factor
  • proto-oncogene c-Myc
  • transcription factor p64
  • v-myc myelocytomatosis viral oncogene homolog
  • c-myc proto-oncogene
  • avian myelocytomatosis viral (v-myc) oncogene homolog
  • c-Myc
  • nucleolar protein 3
  • Avian myelocytomatosis viral (v-myc) oncogene homolog
  • myelocytomatosis viral oncogene homolog
  • v-myc avian myelocytomatosis viral oncogene homolog
  • cellular myelocytomatosis oncogene
  • Proto-oncogene c-Myc
  • Transcription factor p64
  • C-Myc1
  • c-Myc-A
  • cmyca
  • transcriptional regulator Myc-A
  • MYC II
  • transcriptional regulator Myc-B
  • c-Myc I
  • Myc proto-oncogene protein
  • C-Myc2
  • c-Myc-B
  • cmycb
  • CG10798 gene product from transcript CG10798-RB
  • CG10798-PA
  • CG10798-PB
  • Diminutive protein
  • Myc-PA
  • Myc-PB
  • dMyc1
  • diminuitive
  • diminutive
  • lethal (1) G0354
  • lethal (1) G0359
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