C5 抗体
(Complement Component 5 (C5))
The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to a susceptibility to liver fibrosis and to rheumatoid arthritis. [provided by RefSeq, Jul 2008].
recommended
recommended
C5 适用: 人, 小鼠 WB, ELISA, IF (p), IF (cc), IHC (p) 宿主: 兔 Polyclonal unconjugated
recommended
C5 抗体 by 适用
Find C5 抗体 for a variety of species such as anti-Human C5, anti-Mouse C5, anti-Rat C5. The species listed below are among those available. Click on a link to go to the corresponding products.
C5 抗体 by 抗体来源
Find C5 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
C5 抗体 by 克隆形成能力
Find available monoclonal or polyclonal C5 抗体. Click on a link to go to the corresponding products.
C5 抗体 by 克隆
Find C5 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
Popular C5 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse, Rat
Application
WB, IHC (p)
Validations
- (6)
Cat. No.
ABIN3044294
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IF (p), IF (cc), IHC (p)
Validations
- (1)
- (3)
Cat. No.
ABIN727875
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS
Validations
- (5)
Cat. No.
ABIN3029690
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (1)
- (3)
Cat. No.
ABIN652518
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN2856818
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN3043765
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (3)
Cat. No.
ABIN5537708
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN560121
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IA
Validations
- (3)
Cat. No.
ABIN2191948
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IA
Validations
- (1)
Cat. No.
ABIN2191951
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF (p), IF (cc), IHC (p), IHC (fro), ICC
Validations
Cat. No.
ABIN6989472
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF (p), IF (cc), IHC (p), IHC (fro), ICC
Validations
Cat. No.
ABIN6989140
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF (p), IHC (p)
Validations
Cat. No.
ABIN1713727
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC (p)
Validations
Cat. No.
ABIN727877
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN6982560
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our C5 抗体
: "SAK-HV Triggered a Short-period Lipid-lowering Biotherapy Based on the Energy Model of Liver Proliferation via a Novel Pathway." in: Theranostics, Vol. 7, Issue 6, pp. 1749-1769, (2018) (PubMed).: "Complement C5a Receptor is the Key Initiator of Neutrophil Adhesion Igniting Immune Complex-induced Arthritis." in: Science immunology, Vol. 2, Issue 7, (2017) (PubMed).
: "Pre-neutralization of C5a-mediated effects by the monoclonal antibody 137-26 reacting with the C5a moiety of native C5 without preventing C5 cleavage." in: Clinical and experimental immunology, Vol. 133, Issue 2, pp. 160-9, (2003) (PubMed).
: "Essential role of the C5a receptor in E coli-induced oxidative burst and phagocytosis revealed by a novel lepirudin-based human whole blood model of inflammation." in: Blood, Vol. 100, Issue 5, pp. 1869-77, (2002) (PubMed).
: "Identification of complement factor 5 as a susceptibility locus for experimental allergic asthma." in: Nature immunology, Vol. 1, Issue 3, pp. 221-6, (2001) (PubMed).
: "Analysis of the C5a anaphylatoxin core domain using a C5a phage library selected on differentiated U937 cells." in: Molecular immunology, Vol. 36, Issue 2, pp. 145-52, (1999) (PubMed).
: "Epitope mapping of a C5a neutralizing mAb using a combined approach of phage display, synthetic peptides and site-directed mutagenesis." in: Immunotechnology : an international journal of immunological engineering, Vol. 2, Issue 2, pp. 115-26, (1997) (PubMed).
: "Identification of a human C5 beta-chain epitope exposed in the native complement component but concealed in the SC5b-9 complex." in: Scandinavian journal of immunology, Vol. 28, Issue 3, pp. 307-12, (1988) (PubMed).
: "Detection of native human complement components C3 and C5 and their primary activation peptides C3a and C5a (anaphylatoxic peptides) by ELISAs with monoclonal antibodies." in: Journal of immunological methods, Vol. 111, Issue 2, pp. 241-52, (1988) (PubMed).
Aliases for C5 抗体
complement C5 (C5) 抗体complement component 5 (c5) 抗体
complement component 5 (C5) 抗体
hemolytic complement (Hc) 抗体
C5 抗体
C5a 抗体
C5b 抗体
CPAMD4 抗体
Hc 抗体
He 抗体
LOC565774 抗体
RGD1561905 抗体
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