C-Type Lectin Domain Family 6, Member A 产品
(C-Type Lectin Domain Family 6, Member A (CLEC6A))
Categories
Binds high-mannose carbohydrates in a Ca(2+)-dependent manner. Functionnal receptor for alpha-mannans on C. albicans hypheas. Plays an important role in the host defense against C. albicans infection by inducing TH17 cell differentiation. Recognizes also, in a manose dependent manner, allergens from house dust mite and fungi, by promoting cysteinyl leukotriene production. Recognizes soluble elements from the eggs of Shistosoma mansoni altering adaptative immune responses. Transduces signals through an Fc receptor gamma chain /FCER1G and Syk-CARD9-NF-kappa-B-dependent pathway.
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Featured C-Type Lectin Domain Family 6, Member A Categories
C-Type Lectin Domain Family 6, Member A 抗体
High quality antibodies with extensive validation data.
C-Type Lectin Domain Family 6, Member A ELISA试剂盒
Reliable ELISA kits for a wide range of species.
C-Type Lectin Domain Family 6, Member A 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended C-Type Lectin Domain Family 6, Member A 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7186528
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, FACS, IHC (p)
Validations
- (3)
Cat. No.
ABIN959984
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, ICC
Validations
- (2)
Cat. No.
ABIN6260891
Quantity
100 μL
Datasheet
Datasheet
Recommended C-Type Lectin Domain Family 6, Member A ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6730425
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4882590
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6385418
Quantity
96 tests
Datasheet
Datasheet
Recommended C-Type Lectin Domain Family 6, Member A 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7320341
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
Cat. No.
ABIN2745635
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3115618
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our C-Type Lectin Domain Family 6, Member A Products
: "Phenotypic and functional consequences of different isolation protocols on skin mononuclear phagocytes." in: Journal of leukocyte biology, Vol. 101, Issue 6, pp. 1393-1403, (2017) (PubMed).: "Expression of antimicrobial peptides and toll-like receptors is increased in tinea and pityriasis versicolor." in: Mycoses, Vol. 57, Issue 3, pp. 147-52, (2014) (PubMed).
: "Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes." in: The Journal of experimental medicine, Vol. 208, Issue 3, pp. 593-604, (2011) (PubMed).
: "Selective C-Rel activation via Malt1 controls anti-fungal T(H)-17 immunity by dectin-1 and dectin-2." in: PLoS pathogens, Vol. 7, Issue 1, pp. e1001259, (2011) (PubMed).
: "Pathways regulating cytosolic phospholipase A2 activation and eicosanoid production in macrophages by Candida albicans." in: The Journal of biological chemistry, Vol. 285, Issue 40, pp. 30676-85, (2010) (PubMed).
: "Dectin-2 is predominantly myeloid restricted and exhibits unique activation-dependent expression on maturing inflammatory monocytes elicited in vivo." in: European journal of immunology, Vol. 35, Issue 7, pp. 2163-74, (2005) (PubMed).
Synonyms and alternative names related to C-Type Lectin Domain Family 6, Member A
C-type lectin domain containing 6A (CLEC6A), C-type lectin domain family 6, member A (Clec6a), CLEC4N, CLEC6A, CLECSF10Protein level used designations for C-Type Lectin Domain Family 6, Member A
- C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 10
- C-type lectin domain family 6 member A
- C-type lectin superfamily member 10
- DC-associated C-type lectin 2
- dectin 2
- dectin-2
- dendritic cell-associated C-type lectin 2
- C-type lectin domain family 6, member A
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