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C-Raf Proto-Oncogene Serine/Threonine Protein Kinase 产品

(C-Raf Proto-Oncogene Serine/Threonine Protein Kinase (CRAF))
This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. [provided by RefSeq, Jul 2008].

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Featured C-Raf Proto-Oncogene Serine/Threonine Protein Kinase Categories

C-Raf Proto-Oncogene Serine/Threonine Protein Kinase 抗体

High quality antibodies with extensive validation data.

C-Raf Proto-Oncogene Serine/Threonine Protein Kinase ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Recommended C-Raf Proto-Oncogene Serine/Threonine Protein Kinase 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC, WB, ICC
Validations
  • (2)
Cat. No. ABIN1858489
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, WB, IP, IF/ICC
Validations
Cat. No. ABIN6332232
Quantity 1 mL
Datasheet Datasheet

Recommended C-Raf Proto-Oncogene Serine/Threonine Protein Kinase ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1569161
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5652411
Quantity 96 tests
Datasheet Datasheet

Recommended C-Raf Proto-Oncogene Serine/Threonine Protein Kinase 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7396073
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3009008
Quantity 100 μg
Datasheet Datasheet

Synonyms and alternative names related to C-Raf Proto-Oncogene Serine/Threonine Protein Kinase

Raf-1 proto-oncogene, serine/threonine kinase (RAF1), c-Raf, CRAF, NS5, Raf-1

Protein level used designations for C-Raf Proto-Oncogene Serine/Threonine Protein Kinase

  • Oncogene RAF1
  • RAF proto-oncogene serine/threonine-protein kinase
  • proto-oncogene c-RAF
  • raf proto-oncogene serine/threonine protein kinase
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