Catechol-O-Methyltransferase 抗体
(Catechol-O-Methyltransferase (COMT))
Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. [provided by RefSeq, Sep 2008].
recommended
Verified COMT 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
recommended
recommended
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Popular Catechol-O-Methyltransferase 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (6)
Cat. No.
ABIN185682
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS
Validations
- (5)
Cat. No.
ABIN185328
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (1)
- (4)
Cat. No.
ABIN2854980
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p), ICC
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- (8)
Cat. No.
ABIN3043815
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (4)
Cat. No.
ABIN560435
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
- (3)
Cat. No.
ABIN7436675
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
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Cat. No.
ABIN514524
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
- (2)
Cat. No.
ABIN514522
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Bat, Cow, Human, Monkey, Mouse, Pig, Rat
Application
IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN768668
Quantity
50 μg
Datasheet
Datasheet
Reactivity
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Application
IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN768669
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (3)
Cat. No.
ABIN1679321
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7127433
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (5)
- (1)
Cat. No.
ABIN1882224
Quantity
0.1 mL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF, ICC
Validations
- (1)
- (1)
Cat. No.
ABIN6258028
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application
WB
Validations
- (3)
Cat. No.
ABIN2781821
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our Catechol-O-Methyltransferase 抗体
: "m6A Demethylase FTO Regulates Dopaminergic Neurotransmission Deficits Caused by Arsenite." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 165, Issue 2, pp. 431-446, (2018) (PubMed).: "Inhibitory Effect of Bovine Lactoferrin on Catechol-O-Methyltransferase." in: Molecules (Basel, Switzerland), Vol. 22, Issue 8, (2018) (PubMed).
: "Intrarenal dopamine modulates progressive angiotensin II-mediated renal injury." in: American journal of physiology. Renal physiology, Vol. 302, Issue 6, pp. F742-9, (2012) (PubMed).
: "Disturbed expression of phase I and phase II estrogen-metabolizing enzymes in endometrial cancer: lower levels of CYP1B1 and increased expression of S-COMT." in: Molecular and cellular endocrinology, Vol. 331, Issue 1, pp. 158-67, (2010) (PubMed).
: "Chiral Brønsted acid catalyzed enantioselective addition of alpha-isocyanoacetamides to aldehydes." in: Organic letters, Vol. 12, Issue 10, pp. 2414-7, (2010) (PubMed).
: "Impact of aerobic exercise training on cognitive functions and affect associated to the COMT polymorphism in young adults." in: Neurobiology of learning and memory, Vol. 94, Issue 3, pp. 364-72, (2010) (PubMed).
: "Genetic polymorphism of catechol-O-methyltransferase and cytochrome P450c17α in preeclampsia." in: Pharmacogenetics and genomics, Vol. 20, Issue 10, pp. 605-10, (2010) (PubMed).
: "Association between Novelty Seeking of opiate-dependent patients and the catechol-O-methyltransferase Val(158)Met polymorphism." in: Comprehensive psychiatry, Vol. 51, Issue 5, pp. 510-5, (2010) (PubMed).
: "Effects of modafinil on the sleep EEG depend on Val158Met genotype of COMT." in: Sleep, Vol. 33, Issue 8, pp. 1027-35, (2010) (PubMed).
: "Intrarenal dopamine attenuates deoxycorticosterone acetate/high salt-induced blood pressure elevation in part through activation of a medullary cyclooxygenase 2 pathway." in: Hypertension (Dallas, Tex. : 1979), Vol. 54, Issue 5, pp. 1077-83, (2009) (PubMed).
Aliases for Catechol-O-Methyltransferase 抗体
catechol-O-methyltransferase (COMT) 抗体catechol-O-methyltransferase (Comt) 抗体
microRNA 4761 (MIR4761) 抗体
catechol-O-methyltransferase (comt) 抗体
catechol-O-methyltransferase (comt.2) 抗体
catechol-O-methyltransferase S homeolog (comt.S) 抗体
methyltransferase (Rv1703c) 抗体
catechol-o-methyltransferase (Mb1729c) 抗体
catechol-O-methyltransferase a (comta) 抗体
catechol-O-methyltransferase b (comtb) 抗体
catechol O-methyltransferase (LOC100354142) 抗体
COMT 抗体
comt 抗体
Comt1 抗体
D16Wsu103e 抗体
D330014B15Rik 抗体
mb-comt 抗体
MGC154444 抗体
s-comt 抗体
si:dkey-13a21.15 抗体
zgc:114157 抗体
zgc:162236 抗体
zK13A21.15 抗体
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