电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

CASR 产品

(Calcium-Sensing Receptor (CASR))

Categories

The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq, Jul 2008].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured CASR Categories

CASR 抗体

High quality antibodies with extensive validation data.

CASR ELISA试剂盒

Reliable ELISA kits for a wide range of species.

CASR 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CASR 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (1)
  • (4)
Cat. No. ABIN1678994
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, ICC
Validations
  • (4)
Cat. No. ABIN6255749
Quantity 100 μL
Datasheet Datasheet
Reactivity Pig
Application WB, ELISA
Validations
  • (2)
  • (2)
Cat. No. ABIN1386858
Quantity 100 μL
Datasheet Datasheet

Recommended CASR ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6954279
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6954278
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6954280
Quantity 96 tests
Datasheet Datasheet

Recommended CASR 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348127
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348129
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505157
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CASR Products

Issa, Hénaut, Abdallah, Boudot, Lenglet, Avondo, Ibrik, Caus, Brazier, Mentaverri, Zibara, Kamel: "Activation of the calcium-sensing receptor in human valvular interstitial cells promotes calcification." in: Journal of molecular and cellular cardiology, Vol. 129, pp. 2-12, (2019) (PubMed).

Luchsinger, Strikoudis, Danzl, Bush, Finlayson, Satwani, Sykes, Yazawa, Snoeck: "Harnessing Hematopoietic Stem Cell Low Intracellular Calcium Improves Their Maintenance In Vitro." in: Cell stem cell, Vol. 25, Issue 2, pp. 225-240.e7, (2019) (PubMed).

Bächinger, Egli, Goosmann, Monge Naldi, Eckhard: "Immunolocalization of calcium sensing and transport proteins in the murine endolymphatic sac indicates calciostatic functions within the inner ear." in: Cell and tissue research, (2019) (PubMed).

Liu, Tan, Huang, Li, Wang, Liao, Guan, Ji, Yin: "Involvement of calcium-sensing receptor activation in the alleviation of intestinal inflammation in a piglet model by dietary aromatic amino acid supplementation." in: The British journal of nutrition, Vol. 120, Issue 12, pp. 1321-1331, (2019) (PubMed).

Frees, Breuksch, Haber, Bauer, Chavez-Munoz, Raven, Moskalev, D Costa, Tan, Daugaard, Thüroff, Haferkamp, Prawitt, So, Brenner: "Calcium-sensing receptor (CaSR) promotes development of bone metastasis in renal cell carcinoma." in: Oncotarget, Vol. 9, Issue 21, pp. 15766-15779, (2018) (PubMed).

Yuan, Shi, Li, Yang, Tang, Hu, Du, Li, Gu, Wang, Xi, Tang: "Evaluation of a TPTX model induced by ischemia." in: Experimental animals, Vol. 66, Issue 4, pp. 345-356, (2018) (PubMed).

Boudot, Hénaut, Thiem, Geraci, Galante, Saldanha, Saidak, Six, Clézardin, Kamel, Mentaverri et al.: "Overexpression of a functional calcium-sensing receptor dramatically increases osteolytic potential of MDA-MB-231 cells in a mouse model of bone metastasis through epiregulin-mediated osteoprotegerin ..." in: Oncotarget, Vol. 8, Issue 34, pp. 56460-56472, (2017) (PubMed).

Yasukawa, Hayashi, Tanabe, Tsuda, Suzuki, Kawato, Suzuki, Maeno, Ogiso: "Involvement of the calcium-sensing receptor in mineral trioxide aggregate-induced osteogenic gene expression in murine MC3T3-E1 cells." in: Dental materials journal, Vol. 36, Issue 4, pp. 469-475, (2017) (PubMed).

Zeng, Zhu, Xiao, Liu, Sun, Liu, Hao, Lu, Zhang, Li, Wang, Wei, Hu: "Hypoxia-Induced Mitogenic Factor Acts as a Nonclassical Ligand of Calcium-Sensing Receptor, Therapeutically Exploitable for Intermittent Hypoxia-Induced Pulmonary Hypertension." in: Hypertension (Dallas, Tex. : 1979), Vol. 69, Issue 5, pp. 844-854, (2017) (PubMed).

Xiao, Su, Feng, Sun, Liu, Zhang, Lu, Li, Wang, Zhu, Hu: "Monocrotaline Induces Endothelial Injury and Pulmonary Hypertension by Targeting the Extracellular Calcium-Sensing Receptor." in: Journal of the American Heart Association, Vol. 6, Issue 4, (2017) (PubMed).

Synonyms and alternative names related to CASR

calcium sensing receptor (CASR), calcium-sensing receptor (Casr), calcium-sensing receptor L homeolog (casr.L), calcium sensing receptor (Casr), CAR, CaR, CASR, EIG8, FHH, FIH, GPRC2A, Gprc2a, gprc2a, HHC, HHC1, HYPOC1, NSHPT, PCAR1, xV2R F-1

Protein level used designations for CASR

  • extracellular calcium-sensing receptor
  • parathyroid Ca(2+)-sensing receptor 1
  • parathyroid cell calcium-sensing receptor
  • G protein coupled receptor, family C, group 2, member A
  • G protein-coupled receptor, family C, group 2, member A
  • PCaR1
  • cation sensing receptor
  • Calcium-sensing receptor (hypocalciuric hypercalcemia 1 severe neonatal hyperparathyroidism)
  • Calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism)
  • parathyroid Cell calcium-sensing receptor
  • calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism)
  • calcium-sensing receptor
  • vomeronasal receptor F-1
  • parathyroid gland calcium-sensing receptor
  • extracellular calcium-sensing receptor-like
You are here:
客服