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Caspase 6 蛋白

(Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. [provided by RefSeq, Jul 2008].
Caspase 6 Protein (AA 26-125) (GST tag) Caspase 6 Protein (AA 26-125) (GST tag) Caspase 6 Protein (AA 26-125) (GST tag) (ABIN1348111)

CASP6 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

Caspase 6 Protein (AA 81-179) (His tag) (ABIN7400309)

CASP6 宿主: Cow 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, Imm, PC

Caspase 6 Protein (AA 194-293) (His tag) (ABIN7396214)

CASP6 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, Imm, PC

Caspase 6 蛋白 by Origin

Find Caspase 6 蛋白 for a variety of species such as anti-Cow Caspase 6, anti-Human Caspase 6, anti-Rat Caspase 6. The species listed below are among those available. Click on a link to go to the corresponding products.

Caspase 6 蛋白 by Source

Here you will find Caspase 6 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Caspase 6 蛋白 by 蛋白类型

Here you can find Caspase 6 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

Caspase 6 蛋白 by 应用范围

Find Caspase 6 蛋白 validated for a specific application such as WB, ELISA, SDS, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Caspase 6 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348111
Quantity 10 μg
Datasheet Datasheet
Reactivity Cow
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7400309
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7396214
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7402139
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3008670
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow
Source Yeast
Validations
Cat. No. ABIN1628174
Quantity 1 mg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1475590
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN6302847
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Caspase 6 蛋白

Zhou, Li, Tian, Wang, Ding, Pang: "Changes in phosphatidylinositol 3-kinase 55 kDa gamma expression and subcellular localization may be caspase 6 dependent in paraquat-induced SH-SY5Y apoptosis." in: Human & experimental toxicology, Vol. 33, Issue 7, pp. 761-71, (2015) (PubMed).

Xia, Yang, Bu, Ji, Zhao, Zheng, Lin, Li, Lu: "Differential regulation of c-Jun protein plays an instrumental role in chemoresistance of cancer cells." in: The Journal of biological chemistry, Vol. 288, Issue 27, pp. 19321-9, (2013) (PubMed).

Kobayashi, Nolan, Naveed, Hoshino, Segal, Fujita, Rom, Weiden: "Neutrophils activate alveolar macrophages by producing caspase-6-mediated cleavage of IL-1 receptor-associated kinase-M." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 1, pp. 403-10, (2010) (PubMed).

Murakami, Tolstykh, Bao, Niu, Steuer, Bao, Chang, Espiritu, Bansal, Lam, Otto, Sofia, Furman: "Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34337-47, (2010) (PubMed).

Chen, Xia, Fang, Hawke, Lu: "Caspase-10-mediated heat shock protein 90 beta cleavage promotes UVB irradiation-induced cell apoptosis." in: Molecular and cellular biology, Vol. 29, Issue 13, pp. 3657-64, (2009) (PubMed).

Hasegawa, Yamada, Komiyama, Hayashi, Ishibashi, Sunazuka, Izuhara, Sugahara, Tsuruda, Masuda, Takasu, Tsukasaki, Tomonaga, Kamihira et al.: "A novel natural compound, a cycloanthranilylproline derivative (Fuligocandin B), sensitizes leukemia cells to apoptosis induced by tumor necrosis factor related apoptosis-inducing ligand (TRAIL) ..." in: Blood, Vol. 110, Issue 5, pp. 1664-74, (2007) (PubMed).

Zandy, Lakhani, Zheng, Flavell, Bassnett: "Role of the executioner caspases during lens development." in: The Journal of biological chemistry, Vol. 280, Issue 34, pp. 30263-72, (2005) (PubMed).

Basu, Lu, Sun, Moor, Akkaraju, Huang: "Proteolytic activation of protein kinase C-epsilon by caspase-mediated processing and transduction of antiapoptotic signals." in: The Journal of biological chemistry, Vol. 277, Issue 44, pp. 41850-6, (2002) (PubMed).

Aliases for Caspase 6 蛋白

caspase 6 L homeolog (casp6.L) 蛋白
caspase 6 (casp6) 蛋白
caspase 6, apoptosis-related cysteine peptidase (casp6) 蛋白
group XIIA secretory phospholipase A2 (CASP6) 蛋白
caspase-6 (CpipJ_CPIJ017008) 蛋白
caspase 6 (Casp6) 蛋白
caspase 6 (CASP6) 蛋白
CASP6 蛋白
casp6 蛋白
caspase-6 蛋白
mCASP-6 蛋白
mch2 蛋白
Mch2 蛋白
MCH2 蛋白
xCaspase-6 蛋白
zgc:112960 蛋白
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