Caspase 12 (Gene/pseudogene) 抗体
(Caspase 12 (Gene/pseudogene) (CASP12))
Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Feb 2011].
recommended
CASP12 适用: 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
recommended
recommended
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Popular Caspase 12 (Gene/pseudogene) 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse, Rat
Application
WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (8)
- (5)
Cat. No.
ABIN737736
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (10)
Cat. No.
ABIN7442993
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7440263
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS, IF
Validations
- (7)
Cat. No.
ABIN3030291
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (5)
Cat. No.
ABIN3030292
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7156146
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN462331
Quantity
0.05 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (3)
Cat. No.
ABIN6137956
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p), IF
Validations
- (4)
Cat. No.
ABIN655966
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p), IF, IP
Validations
- (4)
Cat. No.
ABIN567795
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p), IF, EIA
Validations
- (4)
Cat. No.
ABIN951051
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7445852
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7177077
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (1)
Cat. No.
ABIN7213960
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN1049503
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Caspase 12 (Gene/pseudogene) 抗体
: "Modulation of mitochondrial phenotypes by endurance exercise contributes to neuroprotection against a MPTP-induced animal model of PD." in: Life sciences, Vol. 209, pp. 455-465, (2018) (PubMed).: "Ibutilide treatment protects against ER stress induced apoptosis by regulating calumenin expression in tunicamycin treated cardiomyocytes." in: PLoS ONE, Vol. 12, Issue 4, pp. e0173469, (2017) (PubMed).
: "Gypenoside Protects against Myocardial Ischemia-Reperfusion Injury by Inhibiting Cardiomyocytes Apoptosis via Inhibition of CHOP Pathway and Activation of PI3K/Akt Pathway In Vivo and In Vitro." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 39, Issue 1, pp. 123-36, (2016) (PubMed).
: "Ibutilide protects against cardiomyocytes injury via inhibiting endoplasmic reticulum and mitochondrial stress pathways." in: Heart and vessels, (2016) (PubMed).
: "Sulfiredoxin-1 exerts anti-apoptotic and neuroprotective effects against oxidative stress-induced injury in rat cortical astrocytes following exposure to oxygen-glucose deprivation and hydrogen ..." in: International journal of molecular medicine, Vol. 36, Issue 1, pp. 43-52, (2015) (PubMed).
: "Increased expression of 78 kD glucose-regulated protein promotes cardiomyocyte apoptosis in a rat model of liver cirrhosis." in: International journal of clinical and experimental pathology, Vol. 8, Issue 8, pp. 9256-63, (2015) (PubMed).
: "Glucose-regulated protein 78 may play a crucial role in promoting the pulmonary microvascular remodeling in a rat model of hepatopulmonary syndrome." in: Gene, Vol. 545, Issue 1, pp. 156-62, (2014) (PubMed).
: "Evodiamine induces G2/M arrest and apoptosis via mitochondrial and endoplasmic reticulum pathways in H446 and H1688 human small-cell lung cancer cells." in: PLoS ONE, Vol. 9, Issue 12, pp. e115204, (2014) (PubMed).
: "Neuroprotection by (-)-epigallocatechin-3-gallate in a rat model of stroke is mediated through inhibition of endoplasmic reticulum stress." in: Molecular medicine reports, Vol. 9, Issue 1, pp. 69-76, (2014) (PubMed).
: "Atmospheric pressure room temperature plasma jets facilitate oxidative and nitrative stress and lead to endoplasmic reticulum stress dependent apoptosis in HepG2 cells." in: PLoS ONE, Vol. 8, Issue 8, pp. e73665, (2013) (PubMed).
Aliases for Caspase 12 (Gene/pseudogene) 抗体
caspase 12 (Casp12) 抗体caspase 12 (CASP12) 抗体
caspase 12 (gene/pseudogene) (CASP12) 抗体
CASP-12 抗体
CASP12P1 抗体
Caspase-12 抗体
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