Caspase 1 抗体
(Caspase 1 (CASP1))
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012].
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Caspase 1 抗体 by 适用
Find Caspase 1 抗体 for a variety of species such as anti-Human Caspase 1, anti-Mouse Caspase 1, anti-Rat Caspase 1. The species listed below are among those available. Click on a link to go to the corresponding products.
Caspase 1 抗体 by 应用范围
Find Caspase 1 抗体 validated for a specific application such as WB, IHC, ELISA, IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.
Caspase 1 抗体 by 抗体来源
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Caspase 1 抗体 by 克隆形成能力
Find available monoclonal or polyclonal Caspase 1 抗体. Click on a link to go to the corresponding products.
Caspase 1 抗体 by 克隆
Find Caspase 1 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
Caspase 1 抗体 by 标记
Find Caspase 1 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
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Application
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Datasheet
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Application
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Cat. No.
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Quantity
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Datasheet
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Cat. No.
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Quantity
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Datasheet
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Cat. No.
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Quantity
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Datasheet
Datasheet
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Application
WB, ELISA, IHC (p)
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Cat. No.
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Quantity
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Quantity
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Quantity
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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- (2)
Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Quantity
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Datasheet
Datasheet
Latest Publications for our Caspase 1 抗体
: "XIST Inhibition Attenuates Calcium Oxalate Nephrocalcinosis-Induced Renal Inflammation and Oxidative Injury via the miR-223/NLRP3 Pathway." in: Oxidative medicine and cellular longevity, Vol. 2021, pp. 1676152, (2022) (PubMed).: "Efficient and Consistent Orthotopic Osteosarcoma Model by Cell Sheet Transplantation in the Nude Mice for Drug Testing." in: Frontiers in bioengineering and biotechnology, Vol. 9, pp. 690409, (2021) (PubMed).
: "Enhanced Autolysosomal Function Ameliorates the Inflammatory Response Mediated by the NLRP3 Inflammasome in Alzheimer's Disease." in: Frontiers in aging neuroscience, Vol. 13, pp. 629891, (2021) (PubMed).
: "HMGB1 participates in LPS‑induced acute lung injury by activating the AIM2 inflammasome in macrophages and inducing polarization of M1 macrophages via TLR2, TLR4, and RAGE/NF‑κB signaling pathways." in: International journal of molecular medicine, Vol. 45, Issue 1, pp. 61-80, (2020) (PubMed).
: "Preventive effect of bergenin against the development of TNBS-induced acute colitis in rats is associated with inflammatory mediators inhibition and NLRP3/ASC inflammasome signaling pathways." in: Chemico-biological interactions, Vol. 297, pp. 25-33, (2019) (PubMed).
: "Caspase-8 Collaborates with Caspase-11 to Drive Tissue Damage and Execution of Endotoxic Shock. ..." in: Immunity, Vol. 49, Issue 1, pp. 42-55.e6, (2019) (PubMed).
: "Platelet activating factor receptor regulates colitis-induced pulmonary inflammation through the NLRP3 inflammasome." in: Mucosal immunology, Vol. 12, Issue 4, pp. 862-873, (2019) (PubMed).
: "Whole Body Vibration Therapy after Ischemia Reduces Brain Damage in Reproductively Senescent Female Rats." in: International journal of molecular sciences, Vol. 19, Issue 9, (2019) (PubMed).
: "Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury." in: Frontiers in molecular neuroscience, Vol. 12, pp. 36, (2019) (PubMed).
: "Novel role of NLRP3-inflammasome in regulation of lipogenesis in fasting-induced hepatic steatosis." in: Diabetes, metabolic syndrome and obesity : targets and therapy, Vol. 12, pp. 801-811, (2019) (PubMed).
Aliases for Caspase 1 抗体
caspase 1 (CASP1) 抗体caspase 1 (Casp1) 抗体
caspase 1, apoptosis-related cysteine peptidase (CASP1) 抗体
caspase 4, apoptosis-related cysteine peptidase (CASP4) 抗体
Death caspase-1 (Dcp-1) 抗体
caspase-1 (Caspase1) 抗体
caspase (LOC5564196) 抗体
caspase recruitment domain-containing protein 16 (LOC451519) 抗体
caspase-1 (CASP1) 抗体
caspase 4 (CASP4) 抗体
CASP1 抗体
ccp1 抗体
CG5370 抗体
DCP-1 抗体
dcp-1 抗体
DCP1 抗体
Dcp1 抗体
dcp1 抗体
Dmel\\CG5370 抗体
ICE 抗体
Ice 抗体
IL1BC 抗体
Il1bc 抗体
l(2)01862 抗体
l(2)02132 抗体
P45 抗体
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