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CASC5 蛋白

(Cancer Susceptibility Candidate 5 (CASC5))
The protein encoded by this gene is a component of the multiprotein assembly that is required for creation of kinetochore-microtubule attachments and chromosome segregation. The encoded protein functions as a scaffold for proteins that influence the spindle assembly checkpoint during the eukaryotic cell cycle and it interacts with at least five different kinetochore proteins and two checkpoint kinases. In adults, this gene is predominantly expressed in normal testes, various cancer cell lines and primary tumors from other tissues and is ubiquitously expressed in fetal tissues. This gene was originally identified as a fusion partner with the mixed-lineage leukemia (MLL) gene in t(11\;15)(q23\;q14). Mutations in this gene cause autosomal recessive primary microcephaly-4 (MCPH4). Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described but their biological validity has not been confirmed. [provided by RefSeq, Jan 2013].
CASC5 Protein (AA 3-98) (GST tag) CASC5 Protein (AA 3-98) (GST tag) CASC5 Protein (AA 3-98) (GST tag) (ABIN1348085)

CASC5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

CASC5 Protein (AA 1-230) (His tag) (ABIN7420573)

CASC5 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant >95 % WB, SDS, Imm, PC

CASC5 Protein (AA 1-277) (His tag,GST tag) (ABIN7423420)

CASC5 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % WB, SDS, Imm, PC

CASC5 蛋白 by Origin

Find CASC5 蛋白 for a variety of species such as anti-Human CASC5, anti-Mouse CASC5. The species listed below are among those available. Click on a link to go to the corresponding products.

CASC5 蛋白 by Source

Here you will find CASC5 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

CASC5 蛋白 by 蛋白类型

Here you can find CASC5 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

CASC5 蛋白 by 应用范围

Find CASC5 蛋白 validated for a specific application such as WB, SDS, ELISA, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular CASC5 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348085
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7420573
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7423420
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN6119589
Quantity 100 μg
Datasheet Datasheet

Aliases for CASC5 蛋白

kinetochore scaffold 1 (KNL1) 蛋白
kinetochore scaffold 1 (Knl1) 蛋白
Kinetochore null protein 1 (knl-1) 蛋白
2310043D08Rik 蛋白
5730505K17Rik 蛋白
AF15Q14 蛋白
CT29 蛋白
D40 蛋白
hKNL-1 蛋白
hSpc105 蛋白
KNL1 蛋白
PPP1R55 蛋白
Rad51 蛋白
Spc7 蛋白
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