CARD8 抗体
(Caspase Recruitment Domain Family, Member 8 (CARD8))
The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010].
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CARD8 抗体 by 适用
Find CARD8 抗体 for a variety of species such as anti-Human CARD8, anti-Mouse CARD8, anti-Rat CARD8. The species listed below are among those available. Click on a link to go to the corresponding products.
CARD8 抗体 by 抗体来源
Find CARD8 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
CARD8 抗体 by 抗原表位
Find CARD8 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.
CARD8 抗体 by 克隆形成能力
Find available monoclonal or polyclonal CARD8 抗体. Click on a link to go to the corresponding products.
CARD8 抗体 by 克隆
Find CARD8 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
Popular CARD8 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ICC, IP, FACS, DB
Validations
- (3)
Cat. No.
ABIN930979
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ELISA
Validations
- (2)
Cat. No.
ABIN7146923
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
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Cat. No.
ABIN524838
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (2)
Cat. No.
ABIN524837
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC, ELISA
Validations
- (2)
Cat. No.
ABIN6260461
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, ICC
Validations
- (2)
Cat. No.
ABIN2855381
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN3020898
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, EIA
Validations
- (2)
Cat. No.
ABIN499535
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
Cat. No.
ABIN872848
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (fro), IHC (p)
Validations
Cat. No.
ABIN886503
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF (cc), IF (p)
Validations
Cat. No.
ABIN2811105
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF (cc), IF (p)
Validations
Cat. No.
ABIN4999036
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF (cc), IF (p)
Validations
Cat. No.
ABIN4999037
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF (cc), IF (p)
Validations
Cat. No.
ABIN886507
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF (cc), IF (p)
Validations
Cat. No.
ABIN886500
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our CARD8 抗体
: "Loss-of-function CARD8 mutation causes NLRP3 inflammasome activation and Crohn's disease." in: The Journal of clinical investigation, Vol. 128, Issue 5, pp. 1793-1806, (2018) (PubMed).: "CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis." in: The Journal of biological chemistry, Vol. 277, Issue 16, pp. 13952-8, (2002) (PubMed).
: "TUCAN/CARDINAL and DRAL participate in a common pathway for modulation of NF-kappaB activation." in: FEBS letters, Vol. 521, Issue 1-3, pp. 165-9, (2002) (PubMed).
: "TUCAN, an antiapoptotic caspase-associated recruitment domain family protein overexpressed in cancer." in: The Journal of biological chemistry, Vol. 276, Issue 34, pp. 32220-9, (2001) (PubMed).
: "DRAL is a p53-responsive gene whose four and a half LIM domain protein product induces apoptosis." in: The Journal of cell biology, Vol. 151, Issue 3, pp. 495-506, (2000) (PubMed).
Aliases for CARD8 抗体
caspase recruitment domain family, member 8 (CARD8) 抗体caspase recruitment domain-containing protein 8 (LOC718594) 抗体
caspase recruitment domain family member 8 (CARD8) 抗体
CARD8 抗体
CARDINAL 抗体
DACAR 抗体
DAKAR 抗体
NDPP 抗体
NDPP1 抗体
TUCAN 抗体
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