CARD16 产品
(Caspase Recruitment Domain Family, Member 16 (CARD16))
Categories
Caspase inhibitor. Acts as a regulator of procaspase- 1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro- inflammatory cytokine response. Also able to inhibit CASP1- mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.
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Featured CARD16 Categories
Recommended CARD16 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC
Validations
- (2)
Cat. No.
ABIN7244684
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
Cat. No.
ABIN530261
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (2)
Cat. No.
ABIN566717
Quantity
100 μg
Datasheet
Datasheet
Recommended CARD16 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348045
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3090483
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN2713162
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our CARD16 Products
: "Regulation of IL-1beta generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins." in: Cell death and differentiation, Vol. 8, Issue 6, pp. 649-57, (2001) (PubMed).Synonyms and alternative names related to CARD16
caspase recruitment domain family member 16 (CARD16), COP, COP1, PSEUDO-ICEProtein level used designations for CARD16
- CARD only domain-containing protein 1
- CARD only protein
- caspase recruitment domain-containing protein 16
- caspase-1 dominant-negative inhibitor pseudo-ICE
- caspase-1 inhibitor COP
- pseudo interleukin-1 beta converting enzyme
- pseudo interleukin-1beta converting enzyme
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