CARD11 产品
(Caspase Recruitment Domain Family, Member 11 (CARD11))
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The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008].
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Featured CARD11 Categories
Recommended CARD11 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
Cat. No.
ABIN7266125
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (2)
Cat. No.
ABIN7263125
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, ICC
Validations
- (2)
Cat. No.
ABIN6260459
Quantity
100 μL
Datasheet
Datasheet
Recommended CARD11 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6202319
Quantity
96 tests
Datasheet
Datasheet
Recommended CARD11 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348037
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3090358
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3136496
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our CARD11 Products
: "MiR-539 inhibits thyroid cancer cell migration and invasion by directly targeting CARMA1." in: Biochemical and biophysical research communications, Vol. 464, Issue 4, pp. 1128-33, (2015) (PubMed).: "Phosphorylation of Carma1, but not Bcl10, by Akt regulates TCR/CD28-mediated NF-κB induction and cytokine production." in: Molecular immunology, Vol. 59, Issue 1, pp. 110-6, (2014) (PubMed).
: "T cell receptor-dependent activation of mTOR signaling in T cells is mediated by Carma1 and MALT1, but not Bcl10." in: Science signaling, Vol. 7, Issue 329, pp. ra55, (2014) (PubMed).
: "Signaling by Fyn-ADAP via the Carma1-Bcl-10-MAP3K7 signalosome exclusively regulates inflammatory cytokine production in NK cells." in: Nature immunology, Vol. 14, Issue 11, pp. 1127-36, (2013) (PubMed).
: "MAGUK-controlled ubiquitination of CARMA1 modulates lymphocyte NF-kappaB activity." in: Molecular and cellular biology, Vol. 30, Issue 4, pp. 922-34, (2010) (PubMed).
: "Bcl10 controls TCR- and FcgammaR-induced actin polymerization." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 7, pp. 4373-84, (2007) (PubMed).
: "Regulation of NF-kappaB activation in T cells via association of the adapter proteins ADAP and CARMA1." in: Science (New York, N.Y.), Vol. 316, Issue 5825, pp. 754-8, (2007) (PubMed).
: "MALT1 and the API2-MALT1 fusion act between CD40 and IKK and confer NF-kappa B-dependent proliferative advantage and resistance against FAS-induced cell death in B cells." in: Blood, Vol. 105, Issue 7, pp. 2891-9, (2005) (PubMed).
: "Phosphorylation of the CARMA1 linker controls NF-kappaB activation." in: Immunity, Vol. 23, Issue 6, pp. 561-74, (2005) (PubMed).
: "Overexpression of caspase recruitment domain (CARD) membrane-associated guanylate kinase 1 (CARMA1) and CARD9 in primary gastric B-cell lymphoma." in: Cancer, Vol. 104, Issue 9, pp. 1885-93, (2005) (PubMed).
Synonyms and alternative names related to CARD11
caspase recruitment domain family member 11 (CARD11), caspase recruitment domain family, member 11 (Card11), caspase recruitment domain-containing protein 11 (LOC100550812), caspase recruitment domain family member 11 (card11), caspase recruitment domain family member 11 (Card11), 0610008L17Rik, 2410011D02Rik, BENTA, BIMP3, CARD11, CARMA1, LOC100232755, PPBLProtein level used designations for CARD11
- CARD-containing MAGUK protein 1
- bcl10-interacting maguk protein 3
- carma 1
- caspase recruitment domain-containing protein 11
- caspase recruitment domain family, member 11
- caspase recruitment domain-containing protein 11-like
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