CAMKK2 抗体
(Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))
The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases. [provided by RefSeq, Jul 2012].
recommended
recommended
recommended
CAMKK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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Popular CAMKK2 抗体
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Reactivity
Application
Validations
Cat. No.
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Datasheet
Reactivity
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Quantity
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Cat. No.
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Quantity
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Cat. No.
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Cat. No.
ABIN1882069
Quantity
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Cow, Dog, Guinea Pig, Human, Mouse, Pig, Rabbit, Rat, Zebrafish (Danio rerio)
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Cat. No.
ABIN3030262
Quantity
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WB, IHC (p), FACS, IHC (fro)
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Latest Publications for our CAMKK2 抗体
: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." in: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).: "Hydrogen Sulfide and/or Ammonia Reduces Spermatozoa Motility through AMPK/AKT Related Pathways." in: Scientific reports, Vol. 6, pp. 37884, (2016) (PubMed).
: "Regulation of steroid hormones and energy status with cysteamine and its effect on spermatogenesis." in: Toxicology and applied pharmacology, Vol. 313, pp. 149-158, (2016) (PubMed).
: "The Anticancer Agent, Di-2-Pyridylketone 4,4-Dimethyl-3-Thiosemicarbazone (Dp44mT), Up-Regulates the AMPK-Dependent Energy Homeostasis Pathway in Cancer Cells." in: Biochimica et biophysica acta, Vol. 1863, Issue 12, pp. 2916-2933, (2016) (PubMed).
: "Cyclic AMP Mimics the Anti-ageing Effects of Calorie Restriction by Up-Regulating Sirtuin." in: Scientific reports, Vol. 5, pp. 12012, (2015) (PubMed).
: "A regulatory feedback loop between Ca2+/calmodulin-dependent protein kinase kinase 2 (CaMKK2) and the androgen receptor in prostate cancer progression." in: The Journal of biological chemistry, Vol. 287, Issue 29, pp. 24832-43, (2012) (PubMed).
: "The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis. ..." in: The EMBO journal, Vol. 30, Issue 13, pp. 2719-33, (2011) (PubMed).
: "Regulation of Rac1 by simvastatin in endothelial cells: differential roles of AMP-activated protein kinase and calmodulin-dependent kinase kinase-beta." in: The Journal of biological chemistry, Vol. 284, Issue 22, pp. 14734-43, (2009) (PubMed).
: "Differential gene expression in the bovine corpus luteum during transition from early phase to midphase and its potential role in acquisition of luteolytic sensitivity to prostaglandin F2 alpha." in: Biology of reproduction, Vol. 80, Issue 5, pp. 980-8, (2009) (PubMed).
: "Human Ca2+/calmodulin-dependent protein kinase kinase beta gene encodes multiple isoforms that display distinct kinase activity." in: The Journal of biological chemistry, Vol. 276, Issue 33, pp. 31113-23, (2001) (PubMed).
Aliases for CAMKK2 抗体
calcium/calmodulin dependent protein kinase kinase 2 (CAMKK2) 抗体calcium/calmodulin-dependent protein kinase kinase 2, beta (Camkk2) 抗体
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1 (camk2b1) 抗体
calcium/calmodulin dependent protein kinase II beta (CAMK2B) 抗体
calcium/calmodulin-dependent protein kinase kinase 2, beta (camkk2) 抗体
calcium/calmodulin-dependent protein kinase kinase 2 (Camkk2) 抗体
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