CAMKK2 产品
(Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))
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The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases. [provided by RefSeq, Jul 2012].
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Featured CAMKK2 Categories
CAMKK2 抗体
High quality antibodies with extensive validation data.
CAMKK2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
CAMKK2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CAMKK2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IP
Validations
- (1)
- (6)
Cat. No.
ABIN564643
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (1)
- (4)
Cat. No.
ABIN950067
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN6257983
Quantity
100 μL
Datasheet
Datasheet
Recommended CAMKK2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965332
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6954286
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1124885
Quantity
96 tests
Datasheet
Datasheet
Recommended CAMKK2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1347947
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1347949
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN5508848
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our CAMKK2 Products
: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." in: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).: "Growth inhibition of human gastric adenocarcinoma cells in vitro by STO-609 is independent of calcium/calmodulin-dependent protein kinase kinase-beta and adenosine monophosphate-activated protein ..." in: American journal of translational research, Vol. 8, Issue 2, pp. 1164-71, (2016) (PubMed).
: "Hydrogen Sulfide and/or Ammonia Reduces Spermatozoa Motility through AMPK/AKT Related Pathways." in: Scientific reports, Vol. 6, pp. 37884, (2016) (PubMed).
: "Regulation of steroid hormones and energy status with cysteamine and its effect on spermatogenesis." in: Toxicology and applied pharmacology, Vol. 313, pp. 149-158, (2016) (PubMed).
: "The Anticancer Agent, Di-2-Pyridylketone 4,4-Dimethyl-3-Thiosemicarbazone (Dp44mT), Up-Regulates the AMPK-Dependent Energy Homeostasis Pathway in Cancer Cells." in: Biochimica et biophysica acta, Vol. 1863, Issue 12, pp. 2916-2933, (2016) (PubMed).
: "Cyclic AMP Mimics the Anti-ageing Effects of Calorie Restriction by Up-Regulating Sirtuin." in: Scientific reports, Vol. 5, pp. 12012, (2015) (PubMed).
: "A regulatory feedback loop between Ca2+/calmodulin-dependent protein kinase kinase 2 (CaMKK2) and the androgen receptor in prostate cancer progression." in: The Journal of biological chemistry, Vol. 287, Issue 29, pp. 24832-43, (2012) (PubMed).
: "The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis. ..." in: The EMBO journal, Vol. 30, Issue 13, pp. 2719-33, (2011) (PubMed).
: "Regulation of Rac1 by simvastatin in endothelial cells: differential roles of AMP-activated protein kinase and calmodulin-dependent kinase kinase-beta." in: The Journal of biological chemistry, Vol. 284, Issue 22, pp. 14734-43, (2009) (PubMed).
: "Differential gene expression in the bovine corpus luteum during transition from early phase to midphase and its potential role in acquisition of luteolytic sensitivity to prostaglandin F2 alpha." in: Biology of reproduction, Vol. 80, Issue 5, pp. 980-8, (2009) (PubMed).
Synonyms and alternative names related to CAMKK2
calcium/calmodulin dependent protein kinase kinase 2 (CAMKK2), calcium/calmodulin-dependent protein kinase kinase 2, beta (Camkk2), calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1 (camk2b1), calcium/calmodulin dependent protein kinase II beta (CAMK2B), calcium/calmodulin-dependent protein kinase kinase 2, beta (camkk2), calcium/calmodulin-dependent protein kinase kinase 2 (Camkk2), calcium/calmodulin dependent protein kinase kinase 2 (Camkk2), 6330570N16Rik, AW061083, camk2b, CAMKK, CAMKK2, CAMKKB, fj90d04, mKIAA0787, si:dkey-174n20.2, wu:fj90d04Protein level used designations for CAMKK2
- CAMKK beta protein
- caM-KK 2
- caM-KK beta
- caM-kinase kinase 2
- caM-kinase kinase beta
- calcium/calmodulin-dependent protein kinase beta
- calcium/calmodulin-dependent protein kinase kinase 2
- caMKK 2
- caMKK beta
- calcium/calmodulin-dependent protein kinase kinase beta
- calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1
- protein-tyrosine kinase
- calcium/calmodulin-dependent protein kinase II beta
- calcium/calmodulin-dependent protein kinase kinase 2, beta
- calcium/calmodulin-dependent protein kinase kinase 2-like
- Ca+/Calmodulin-dependent protein kinase kinase beta (CaM-kinase kinase beta)
- CaM-kinase kinase beta
- calcium/calmodulin-dependent protein kinase 2 beta
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