CADM1 抗体
(Cell Adhesion Molecule 1 (CADM1))
Mediates homophilic cell-cell adhesion in a Ca(2+)- independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca(2+)-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. May act as a synaptic cell adhesion molecule that drives synapse assembly. May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.
recommended
recommended
CADM1 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
recommended
CADM1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
CADM1 抗体 by Grade
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CADM1 抗体 by 抗体来源
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CADM1 抗体 by 克隆形成能力
Find available monoclonal or polyclonal CADM1 抗体. Click on a link to go to the corresponding products.
CADM1 抗体 by 克隆
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Popular CADM1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (5)
Cat. No.
ABIN565153
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (2)
- (3)
Cat. No.
ABIN738351
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (4)
Cat. No.
ABIN6260400
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (3)
Cat. No.
ABIN761351
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IF
Validations
- (3)
Cat. No.
ABIN3187364
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (3)
Cat. No.
ABIN3022655
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (2)
Cat. No.
ABIN7185629
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IHC (fro), ICC
Validations
- (2)
Cat. No.
ABIN7435799
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7147246
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN654660
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p), EIA
Validations
- (3)
Cat. No.
ABIN951001
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7180134
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN525371
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN571219
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN870695
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CADM1 抗体
: "Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity." in: International journal of nanomedicine, Vol. 9, pp. 4829-46, (2014) (PubMed).: "Polysialylation of the synaptic cell adhesion molecule 1 (SynCAM 1) depends exclusively on the polysialyltransferase ST8SiaII in vivo." in: The Journal of biological chemistry, Vol. 287, Issue 42, pp. 35170-80, (2012) (PubMed).
: "Aberrant methylation accounts for cell adhesion-related gene silencing during 3-methylcholanthrene and diethylnitrosamine induced multistep rat lung carcinogenesis associated with overexpression of ..." in: Toxicology and applied pharmacology, Vol. 251, Issue 1, pp. 70-8, (2011) (PubMed).
: "SMAGP, a new small trans-membrane glycoprotein altered in cancer." in: Oncogene, Vol. 23, Issue 19, pp. 3395-403, (2004) (PubMed).
: "SynCAM, a synaptic adhesion molecule that drives synapse assembly." in: Science (New York, N.Y.), Vol. 297, Issue 5586, pp. 1525-31, (2002) (PubMed).
Aliases for CADM1 抗体
cell adhesion molecule 1 (CADM1) 抗体cell adhesion molecule 1 L homeolog (cadm1.L) 抗体
cell adhesion molecule 1 (Cadm1) 抗体
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