CACNA1G 产品
(Calcium Channel, Voltage-Dependent, T Type, alpha 1G Subunit (CACNA1G))
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Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death. This gene encodes a T-type, low-voltage activated calcium channel. The T-type channels generate currents that are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing. Many alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Sep 2011].
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CACNA1G 抗体
High quality antibodies with extensive validation data.
Recommended CACNA1G 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
- (1)
- (2)
Cat. No.
ABIN680608
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN1027719
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN2483303
Quantity
100 μg
Datasheet
Datasheet
Recommended CACNA1G ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6213224
Quantity
96 tests
Datasheet
Datasheet
Latest Publications for our CACNA1G Products
: "Eps15 Homology Domain-containing Protein 3 Regulates Cardiac T-type Ca2+ Channel Targeting and Function in the Atria." in: The Journal of biological chemistry, Vol. 290, Issue 19, pp. 12210-21, (2015) (PubMed).: "Mibefradil reduces blood glucose concentration in db/db mice." in: Clinics (São Paulo, Brazil), Vol. 69, Issue 1, pp. 61-7, (2014) (PubMed).
: "Simvastatin potently induces calcium-dependent apoptosis of human leiomyoma cells." in: The Journal of biological chemistry, Vol. 289, Issue 51, pp. 35075-86, (2014) (PubMed).
: "Age-related downregulation of the CaV3.1 T-type calcium channel as a mediator of amyloid beta production." in: Neurobiology of aging, Vol. 35, Issue 5, pp. 1002-11, (2014) (PubMed).
: "Inhibition of T-type calcium channels disrupts Akt signaling and promotes apoptosis in glioblastoma cells." in: Biochemical pharmacology, Vol. 85, Issue 7, pp. 888-97, (2013) (PubMed).
: "NaV1.1 channels in axon initial segments of bipolar cells augment input to magnocellular visual pathways in the primate retina." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 41, pp. 16045-59, (2013) (PubMed).
: "Congenital heart block maternal sera autoantibodies target an extracellular epitope on the α1G T-type calcium channel in human fetal hearts." in: PLoS ONE, Vol. 8, Issue 9, pp. e72668, (2013) (PubMed).
: "Decreased cardiac L-type Ca²? channel activity induces hypertrophy and heart failure in mice." in: The Journal of clinical investigation, Vol. 122, Issue 1, pp. 280-90, (2012) (PubMed).
: "Genetic enhancement of thalamocortical network activity by elevating alpha 1g-mediated low-voltage-activated calcium current induces pure absence epilepsy." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 6, pp. 1615-25, (2009) (PubMed).
: "It takes T to tango." in: Neuron, Vol. 31, Issue 1, pp. 3-4, (2001) (PubMed).
Synonyms and alternative names related to CACNA1G
calcium voltage-gated channel subunit alpha1 G (CACNA1G), calcium channel, voltage-dependent, T type, alpha 1G subunit (cacna1g), calcium channel, voltage-dependent, T type, alpha 1G subunit L homeolog (cacna1g.L), calcium channel, voltage-dependent, T type, alpha 1G subunit (Cacna1g), calcium voltage-gated channel subunit alpha1 G (Cacna1g), a1G, alpha-1G, ca(v)3.1, Ca(v)3.1, Ca(V)T.1, CACNA1G, cav3.1, Cav3.1, Cav3.1d, mKIAA1123, NBR13, [a]1GProtein level used designations for CACNA1G
- voltage-dependent calcium channel alpha 1G subunit
- calcium channel, voltage-dependent, T type, alpha 1G subunit
- calcium channel voltage-dependent T type Cav3.1, alpha 1g subunit
- cav3.1c
- voltage-dependent T-type calcium channel subunit alpha-1G
- voltage-gated calcium channel subunit alpha Cav3.1
- calcium channel, voltage-dependent, alpha 1G subunit
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