BUB1B 产品
(Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B))
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This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq, Jul 2008].
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Featured BUB1B Categories
Recommended BUB1B 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), PLA, RNAi
Validations
- (5)
- (7)
Cat. No.
ABIN560109
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Dog, Human, Monkey, Rat
Application
WB, IF, FACS
Validations
- (6)
Cat. No.
ABIN1496997
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Monkey
Application
WB, IHC, IF, IHC (p)
Validations
- (5)
Cat. No.
ABIN1497002
Quantity
100 μL
Datasheet
Datasheet
Recommended BUB1B 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346985
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346987
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN5508834
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our BUB1B Products
: "PKCε Controls Mitotic Progression by Regulating Centrosome Migration and Mitotic Spindle Assembly." in: Molecular cancer research : MCR, Vol. 16, Issue 1, pp. 3-15, (2019) (PubMed).: "Elucidating the Role of the Maternal Embryonic Leucine Zipper Kinase in Adrenocortical Carcinoma." in: Endocrinology, Vol. 159, Issue 7, pp. 2532-2544, (2019) (PubMed).
: "Chelidonine induces mitotic slippage and apoptotic-like death in SGC-7901 human gastric carcinoma cells." in: Molecular medicine reports, Vol. 13, Issue 2, pp. 1336-44, (2016) (PubMed).
: "Prognostic implications of securin expression and sub-cellular localization in human breast cancer." in: Cellular oncology (Dordrecht), Vol. 39, Issue 4, pp. 319-31, (2016) (PubMed).
: "Plk1 is upregulated in androgen-insensitive prostate cancer cells and its inhibition leads to necroptosis." in: Oncogene, Vol. 32, Issue 24, pp. 2973-83, (2013) (PubMed).
: "Phosphoinositide 3-kinase β regulates chromosome segregation in mitosis." in: Molecular biology of the cell, Vol. 23, Issue 23, pp. 4526-42, (2012) (PubMed).
: "The Ndc80 internal loop is required for recruitment of the Ska complex to establish end-on microtubule attachment to kinetochores." in: Journal of cell science, Vol. 125, Issue Pt 13, pp. 3243-53, (2012) (PubMed).
: "Inhibitory phosphorylation of cyclin-dependent kinase 1 as a compensatory mechanism for mitosis exit." in: Molecular and cellular biology, Vol. 31, Issue 7, pp. 1478-91, (2011) (PubMed).
: "Orderly inactivation of the key checkpoint protein mitotic arrest deficient 2 (MAD2) during mitotic progression." in: The Journal of biological chemistry, Vol. 286, Issue 15, pp. 13052-9, (2011) (PubMed).
: "Determinants of mitotic catastrophe on abrogation of the G2 DNA damage checkpoint by UCN-01." in: Molecular cancer therapeutics, Vol. 10, Issue 5, pp. 784-94, (2011) (PubMed).
Synonyms and alternative names related to BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B (BUB1B), BUB1B, mitotic checkpoint serine/threonine kinase (Bub1b), BUB1 mitotic checkpoint serine/threonine kinase B (Bub1b), BUB1B, mitotic checkpoint serine/threonine kinase L homeolog (bub1b.L), BUB1B, mitotic checkpoint serine/threonine kinase (bub1b), Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (bub1b), Bub1 kinase (Bub1), AU045529, BUB1, bub1, BUB1-like, Bub1A, bub1b, BUB1beta, BUBR1, BubR1, BubRI, CG14030, CG14030/Bub1, Dmel\\CG14030, hBUBR1, MAD3L, MVA1, SSK1Protein level used designations for BUB1B
- MAD3/BUB1-related protein kinase
- budding uninhibited by benzimidazoles 1 homolog beta
- mitotic checkpoint kinase MAD3L
- mitotic checkpoint serine/threonine-protein kinase BUB1 beta
- budding uninhibited by benzimidazoles 1 beta
- budding uninhibited by benzimidazoles 1 homolog, beta
- BUB1 budding uninhibited by benzimidazoles 1 homolog beta
- budding uninhibited by benzimidazoles 1 homolog beta (yeast)
- mitotic checkpoint serine/threonine-protein kinase BUB1 beta-like
- Bub1-PA
- CG14030-PA
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