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BRSK1 蛋白

(BR Serine/threonine Kinase 1 (BRSK1))

Serine/threonine-protein kinase that plays a key role in polarization of neurons and centrosome duplication. Phosphorylates CDC25B, CDC25C, MAPT/TAU, RIMS1, TUBG1, TUBG2 and WEE1. Following phosphorylation and activation by STK11/LKB1, acts as a key regulator of polarization of cortical neurons, probably by mediating phosphorylation of microtubule-associated proteins such as MAPT/TAU at 'Ser-573'. Also regulates neuron polarization by mediating phosphorylation of WEE1 at 'Ser-642' in post-mitotic neurons, leading to down-regulate WEE1 activity in polarized neurons. Also acts as a positive regulator of centrosome duplication by mediating phosphorylation of gamma-tubulin (TUBG1 and TUBG2) at 'Ser-131', leading to translocation of gamma-tubulin and its associated proteins to the centrosome. Involved in the UV- induced DNA damage checkpoint response, probably by inhibiting CDK1 activity through phosphorylation and activation of WEE1, and inhibition of CDC25B and CDC25C (By similarity). In neurons, localizes to synaptic vesicles and plays a role in neurotransmitter release, possibly by phosphorylating RIMS1.

recommended

BRSK1 Protein (AA 289-380) (GST tag) (ABIN1346887)

BRSK1 宿主: 人宿主: 小麦胚 Recombinant ELISA, WB, AA, AP

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recommended

BRSK1 Protein (GST tag) (ABIN5509205)

BRSK1 宿主: 小鼠宿主: Insect Cells Recombinant 70 % - 90 % Func Active

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recommended

BRSK1 Protein (AA 1-778) (Strep Tag) (ABIN3090446)

BRSK1 宿主: 人宿主: Tobacco (Nicotiana tabacum) Recombinant > 80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

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BRSK1 蛋白 by Origin

Find BRSK1 蛋白 for a variety of species such as anti-Human BRSK1, anti-Mouse BRSK1, anti-Rat BRSK1. The species listed below are among those available. Click on a link to go to the corresponding products.

BRSK1 蛋白 by Source

Here you will find BRSK1 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

BRSK1 蛋白 by 蛋白类型

Here you can find BRSK1 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

BRSK1 蛋白 by 应用范围

Find BRSK1 蛋白 validated for a specific application such as ELISA, WB, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

BRSK1 蛋白 by 生物活性

Find BRSK1 蛋白 with a specific 生物活性. The 生物活性 listed below are among those available. Click on a link to go to the corresponding products.

Popular BRSK1 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

BRSK1 Protein (AA 289-380) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1346887

Quantity 10 μg

Datasheet Datasheet

BRSK1 Protein (GST tag)

Reactivity Mouse

Source Insect Cells

Validations

Cat. No. ABIN5509205

Quantity 10 μg

Datasheet Datasheet

BRSK1 Protein (AA 1-778) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3090446

Quantity 1 mg

Datasheet Datasheet

BRSK1 Protein (AA 1-778) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3135216

Quantity 1 mg

Datasheet Datasheet

BRSK1 Protein (AA 1-778) (His tag)

Reactivity Rat

Source Yeast

Validations

Cat. No. ABIN1670475

Quantity 1 mg

Datasheet Datasheet

Aliases for BRSK1 蛋白

BR serine/threonine kinase 1 (BRSK1) 蛋白
BR serine/threonine kinase 1 (Brsk1) 蛋白
BRSK1 蛋白
Gm1100 蛋白
hSAD1 蛋白
RGD1563268 蛋白
SAD-B 蛋白
Sad-b 蛋白
SADB 蛋白

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BRSK1 蛋白 by Origin

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BRSK1 蛋白 by 生物活性

Popular BRSK1 蛋白

Aliases for BRSK1 蛋白

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