BRMS1 产品
(Breast Cancer Metastasis Suppressor 1 (BRMS1))
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This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Featured BRMS1 Categories
BRMS1 抗体
High quality antibodies with extensive validation data.
BRMS1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
BRMS1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended BRMS1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IP
Validations
- (8)
- (5)
Cat. No.
ABIN565191
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
Cat. No.
ABIN7265929
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, ICC
Validations
- (3)
Cat. No.
ABIN6256973
Quantity
100 μL
Datasheet
Datasheet
Recommended BRMS1 ELISA试剂盒
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Reactivity
Analytical Method
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Quantity
Datasheet
Reactivity
Cow
Analytical Method
Validations
Cat. No.
ABIN1124133
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6202158
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6202159
Quantity
96 tests
Datasheet
Datasheet
Recommended BRMS1 蛋白
Latest Publications for our BRMS1 Products
: "Expression of the metastasis suppressor BRMS1 in uveal melanoma." in: Ecancermedicalscience, Vol. 8, pp. 410, (2014) (PubMed).: "BRMS1 suppresses lung cancer metastases through an E3 ligase function on histone acetyltransferase p300." in: Cancer research, Vol. 73, Issue 4, pp. 1308-17, (2013) (PubMed).
: "Low BRMS1 expression promotes nasopharyngeal carcinoma metastasis in vitro and in vivo and is associated with poor patient survival." in: BMC cancer, Vol. 12, pp. 376, (2012) (PubMed).
: "Breast cancer metastasis suppressor 1 (BRMS1) is destabilized by the Cul3-SPOP E3 ubiquitin ligase complex." in: Biochemical and biophysical research communications, Vol. 415, Issue 4, pp. 720-6, (2011) (PubMed).
: "BRMS1 transcriptional repression correlates with CpG island methylation and advanced pathological stage in non-small cell lung cancer." in: The Journal of pathology, Vol. 221, Issue 2, pp. 229-37, (2010) (PubMed).
: "BRMS1 expression alters the ultrastructural, biomechanical and biochemical properties of MDA-MB-435 human breast carcinoma cells: an AFM and Raman microspectroscopy study." in: Cancer letters, Vol. 293, Issue 1, pp. 82-91, (2010) (PubMed).
: "Breast cancer metastasis suppressor 1 (BRMS1) suppresses metastasis and correlates with improved patient survival in non-small cell lung cancer." in: Cancer letters, Vol. 276, Issue 2, pp. 196-203, (2009) (PubMed).
: "Expression of the Breast Cancer Metastasis Suppressor 1 (BRMS1) maintains in vitro chemosensitivity of breast cancer cells." in: Cancer letters, Vol. 281, Issue 1, pp. 100-7, (2009) (PubMed).
: "A shift from nuclear to cytoplasmic breast cancer metastasis suppressor 1 expression is associated with highly proliferative estrogen receptor-negative breast cancers." in: Tumour biology, Vol. 30, Issue 3, pp. 148-59, (2009) (PubMed).
: "BRMS1 contributes to the negative regulation of uPA gene expression through recruitment of HDAC1 to the NF-kappaB binding site of the uPA promoter." in: Clinical & experimental metastasis, Vol. 26, Issue 3, pp. 229-37, (2009) (PubMed).
Synonyms and alternative names related to BRMS1
breast cancer metastasis suppressor 1 (BRMS1), breast cancer metastasis-suppressor 1 (Brms1), breast cancer metastasis suppressor 1 L homeolog (brms1.L), breast cancer metastasis suppressor 1 (Brms1), breast cancer metastasis suppressor 1 (brms1), AV003220, AW554636, BRMS1, BRMS1L, MGC98869, si:zc188c22.3, si:zc194c5.2, wu:fb57b08, zgc:56414Protein level used designations for BRMS1
- breast cancer metastasis-suppressor 1
- breast cancer metastasis suppressor 1
- breast cancer metastasis-suppressor 1 homolog
- breast cancer metastasis-suppressor 1-like protein
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