BRE 抗体
(Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE))
Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it acts as an adapter that bridges the interaction between BABAM1/NBA1 and the rest of the complex, thereby being required for the complex integrity and modulating the E3 ubiquitin ligase activity of the BRCA1-BARD1 heterodimer. Probably also plays a role as a component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin (By similarity).
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recommended
recommended
BRE 抗体 by Grade
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BRE 抗体 by 应用范围
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BRE 抗体 by 抗原表位
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BRE 抗体 by 克隆形成能力
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Popular BRE 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (4)
Cat. No.
ABIN7265912
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, ICC, IP
Validations
- (4)
Cat. No.
ABIN2856093
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7145788
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN6258458
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC, IF, IHC (p), ICC
Validations
- (3)
Cat. No.
ABIN604922
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (2)
Cat. No.
ABIN523069
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Bat, Chicken, Cow, Dog, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Rabbit, Rat, Xenopus laevis, Zebrafish (Danio rerio)
Application
WB, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN6754911
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p), EIA
Validations
- (2)
Cat. No.
ABIN499497
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
Cat. No.
ABIN713591
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN713593
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, IF (cc), IF (p)
Validations
Cat. No.
ABIN4997606
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, IF (cc), IF (p)
Validations
Cat. No.
ABIN885474
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, IF (cc), IF (p)
Validations
Cat. No.
ABIN885476
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, IF (cc), IF (p)
Validations
Cat. No.
ABIN885472
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, IF (cc), IF (p)
Validations
Cat. No.
ABIN2810423
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our BRE 抗体
: "BRE is an antiapoptotic protein in vivo and overexpressed in human hepatocellular carcinoma." in: Oncogene, Vol. 27, Issue 9, pp. 1208-17, (2008) (PubMed).: "A death receptor-associated anti-apoptotic protein, BRE, inhibits mitochondrial apoptotic pathway." in: The Journal of biological chemistry, Vol. 279, Issue 50, pp. 52106-16, (2004) (PubMed).
: "Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair." in: Molecular cell, Vol. 12, Issue 5, pp. 1087-99, (2003) (PubMed).
: "Expression of human BRE in multiple isoforms." in: Biochemical and biophysical research communications, Vol. 288, Issue 3, pp. 535-45, (2001) (PubMed).
: "Identification of a brain- and reproductive-organs-specific gene responsive to DNA damage and retinoic acid." in: Biochemical and biophysical research communications, Vol. 206, Issue 2, pp. 764-74, (1995) (PubMed).
Aliases for BRE 抗体
BRISC and BRCA1 A complex member 2 (babam2) 抗体BRISC and BRCA1 A complex member 2 (BABAM2) 抗体
BRISC and BRCA1 A complex member 2 (Babam2) 抗体
brain and reproductive organ-expressed (TNFRSF1A modulator) (BRE) 抗体
BRISC and BRCA1 A complex member 2 L homeolog (babam2.L) 抗体
6030405P19Rik 抗体
AI429776 抗体
B830038C02Rik 抗体
brcc4 抗体
BRCC4 抗体
brcc45 抗体
BRCC45 抗体
BRE 抗体
im:7141046 抗体
LOC100231620 抗体
zgc:110368 抗体
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