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BRCA1 蛋白

(Breast Cancer 1 (BRCA1))

This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified. [provided by RefSeq, May 2009].

recommended

BRCA1 Protein (AA 1581-1670) (GST tag) (ABIN1346847)

BRCA1 宿主: 人宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

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recommended

BRCA1 Protein (AA 1-59) (GST tag) (ABIN1346845)

BRCA1 宿主: 人宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

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recommended

BRCA1 Protein (AA 1610-1863) (His tag) (ABIN7504943)

BRCA1 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by reducing SDS-PAGE.

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BRCA1 蛋白 by Origin

Find BRCA1 蛋白 for a variety of species such as anti-Human BRCA1, anti-Rat BRCA1, anti-Mouse BRCA1. The species listed below are among those available. Click on a link to go to the corresponding products.

BRCA1 蛋白 by Source

Here you will find BRCA1 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

BRCA1 蛋白 by 蛋白类型

Here you can find BRCA1 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

BRCA1 蛋白 by 应用范围

Find BRCA1 蛋白 validated for a specific application such as WB, SDS, ELISA, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular BRCA1 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

BRCA1 Protein (AA 1581-1670) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1346847

Quantity 10 μg

Datasheet Datasheet

BRCA1 Protein (AA 1-59) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1346845

Quantity 10 μg

Datasheet Datasheet

BRCA1 Protein (AA 1610-1863) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7504943

Quantity 100 μg

Datasheet Datasheet

BRCA1 Protein (AA 1564-1863) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7505164

Quantity 100 μg

Datasheet Datasheet

BRCA1 Protein (AA 1524-1781) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7415059

Quantity 100 μg

Datasheet Datasheet

BRCA1 Protein (AA 1579-1811) (His tag,GST tag)

Reactivity Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7403681

Quantity 100 μg

Datasheet Datasheet

BRCA1 Protein (AA 19-83) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7393967

Quantity 100 μg

Datasheet Datasheet

BRCA1 蛋白

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN2128207

Quantity 100 μg

Datasheet Datasheet

BRCA1 蛋白

Reactivity Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN3008532

Quantity 100 μg

Datasheet Datasheet

BRCA1 Protein (His tag)

Reactivity Human

Source Baculovirus

Validations

Cat. No. ABIN2669409

Quantity 2 μg

Datasheet Datasheet

Aliases for BRCA1 蛋白

BRCA1, DNA repair associated (BRCA1) 蛋白
breast cancer 1 (brca1) 蛋白
breast cancer 1, early onset (LOC755086) 蛋白
breast cancer 1, early onset (Brca1) 蛋白
BRCA1, DNA repair associated (Brca1) 蛋白
breast cancer 1, early onset (BRCA1) 蛋白
breast cancer 1 L homeolog (brca1.L) 蛋白
brca1 蛋白
BRCA1 蛋白
BRCAI 蛋白
brcai 蛋白
BRCC1 蛋白
brcc1 蛋白
BROVCA1 蛋白
IRIS 蛋白
iris 蛋白
LOC100224649 蛋白
PNCA4 蛋白
PPP1R53 蛋白
PSCP 蛋白
pscp 蛋白
RNF53 蛋白
rnf53 蛋白

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BRCA1 蛋白 by Origin

BRCA1 蛋白 by Source

BRCA1 蛋白 by 蛋白类型

BRCA1 蛋白 by 应用范围

Popular BRCA1 蛋白

Aliases for BRCA1 蛋白

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