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BRCA1 ELISA试剂盒

(Breast Cancer 1 (BRCA1))

This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified. [provided by RefSeq, May 2009].

recommended

BRCA1 ELISA 试剂盒 (ABIN6965234)

BRCA1 适用: 人 Colorimetric Sandwich ELISA 0.313 ng/mL - 20 ng/mL Plasma, Serum, Tissue Homogenate

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recommended

BRCA1 ELISA 试剂盒 (ABIN6954188)

BRCA1 适用: 人 Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Cell Lysate, Tissue Homogenate

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recommended

BRCA1 ELISA 试剂盒 (ABIN1124142)

BRCA1 适用: 小鼠 Colorimetric

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Find BRCA1 ELISA试剂盒 for a variety of species such as anti-Human BRCA1, anti-Cow BRCA1, anti-Dog BRCA1. The species listed below are among those available. Click on a link to go to the corresponding products.

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BRCA1 ELISA试剂盒 by Analytical Method

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BRCA1 ELISA试剂盒 by 样本

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BRCA1 ELISA试剂盒 by 抗原表位

Find BRCA1 ELISA试剂盒 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

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