BMPR2 抗体
(Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, Jul 2008].
recommended
recommended
recommended
BMPR2 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
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Reactivity
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Validations
Cat. No.
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Application
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Cat. No.
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Quantity
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Application
WB, ELISA, IHC, ICC
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Cat. No.
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Quantity
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Cat. No.
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Cat. No.
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Quantity
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Cat. No.
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Cat. No.
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Latest Publications for our BMPR2 抗体
: "TGF‑β1 affects the renal cancer miRNome and regulates tumor cells proliferation." in: International journal of molecular medicine, Vol. 49, Issue 4, (2022) (PubMed).: "MicroRNA-155 inhibits the osteogenic differentiation of mesenchymal stem cells induced by BMP9 via downregulation of BMP signaling pathway." in: International journal of molecular medicine, Vol. 41, Issue 6, pp. 3379-3393, (2018) (PubMed).
: "Baicalein attenuates monocrotaline-induced pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition." in: Life sciences, Vol. 207, pp. 442-450, (2018) (PubMed).
: "BMP-7 induces apoptosis in human germinal center B cells and is influenced by TGF-β receptor type I ALK5." in: PLoS ONE, Vol. 12, Issue 5, pp. e0177188, (2017) (PubMed).
: "Endocytosis contributes to BMP2-induced Smad signalling and neuronal growth." in: Neuroscience letters, Vol. 643, pp. 32-37, (2017) (PubMed).
: "Correlating the Effects of Bone Morphogenic Protein to Secreted Soluble Factors from Fibroblasts and Mesenchymal Stem Cells in Regulating Regenerative Processes In Vitro." in: Tissue engineering. Part A, (2014) (PubMed).
: "BMP signaling induces astrocytic differentiation of clinically derived oligodendroglioma propagating cells." in: Molecular cancer research : MCR, Vol. 12, Issue 2, pp. 283-94, (2014) (PubMed).
: "Epigenetic repression of bone morphogenetic protein receptor II expression in scleroderma." in: Journal of cellular and molecular medicine, Vol. 17, Issue 10, pp. 1291-9, (2014) (PubMed).
: "Roles of miR-1-1 and miR-181c in ventricular septal defects." in: International journal of cardiology, Vol. 168, Issue 2, pp. 1441-6, (2013) (PubMed).
: "Bone morphogenetic protein-9 activates Smad and ERK pathways and supports human osteoclast function and survival in vitro." in: Cellular signalling, Vol. 25, Issue 4, pp. 717-28, (2013) (PubMed).
Aliases for BMPR2 抗体
bone morphogenetic protein receptor type 2 (BMPR2) 抗体bone morphogenetic protein receptor, type II b (serine/threonine kinase) (bmpr2b) 抗体
bone morphogenetic protein receptor, type II (serine/threonine kinase) (Bmpr2) 抗体
bone morphogenetic protein receptor type 2 (Bmpr2) 抗体
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