BIN1 抗体
(Bridging Integrator 1 (BIN1))
This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described. [provided by RefSeq, Sep 2011].
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recommended
recommended
BIN1 抗体 by Grade
Find BIN1 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.
BIN1 抗体 by 适用
Find BIN1 抗体 for a variety of species such as anti-Human BIN1, anti-Mouse BIN1, anti-Rat BIN1. The species listed below are among those available. Click on a link to go to the corresponding products.
BIN1 抗体 by 抗体来源
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BIN1 抗体 by 克隆形成能力
Find available monoclonal or polyclonal BIN1 抗体. Click on a link to go to the corresponding products.
BIN1 抗体 by 克隆
Find BIN1 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
Popular BIN1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Rat
Application
WB, IHC, IF
Validations
- (5)
Cat. No.
ABIN7259755
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
Cat. No.
ABIN1678863
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF, ICC, IHC (p)
Validations
- (1)
- (4)
Cat. No.
ABIN2855595
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS
Validations
- (5)
Cat. No.
ABIN5542281
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IP, FACS
Validations
- (2)
- (2)
Cat. No.
ABIN1043735
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IP
Validations
- (2)
- (2)
Cat. No.
ABIN1043739
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7160382
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (2)
Cat. No.
ABIN513324
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN513325
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IP
Validations
- (1)
- (1)
Cat. No.
ABIN1043737
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN5530529
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7184567
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN334360
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB
Validations
- (1)
Cat. No.
ABIN928783
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ICC
Validations
- (2)
Cat. No.
ABIN1866897
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our BIN1 抗体
: "Adverse transverse-tubule remodeling in a rat model of heart failure is attenuated with low-dose triiodothyronine treatment." in: Molecular medicine (Cambridge, Mass.), Vol. 25, Issue 1, pp. 53, (2020) (PubMed).: "FBP17 and CIP4 recruit SHIP2 and lamellipodin to prime the plasma membrane for fast endophilin-mediated endocytosis." in: Nature cell biology, Vol. 20, Issue 9, pp. 1023-1031, (2019) (PubMed).
: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).
: "Mutations in amphiphysin 2 (BIN1) disrupt interaction with dynamin 2 and cause autosomal recessive centronuclear myopathy." in: Nature genetics, Vol. 39, Issue 9, pp. 1134-9, (2007) (PubMed).
: "Bin1 attenuation in breast cancer is correlated to nodal metastasis and reduced survival." in: Cancer biology & therapy, Vol. 6, Issue 2, pp. 192-4, (2007) (PubMed).
: "Human T-cell lymphotrophic virus type I rex and p30 interactions govern the switch between virus latency and replication." in: The Journal of biological chemistry, Vol. 282, Issue 19, pp. 14608-15, (2007) (PubMed).
: "A role for the putative tumor suppressor Bin1 in muscle cell differentiation." in: Molecular and cellular biology, Vol. 18, Issue 1, pp. 566-75, (1998) (PubMed).
: "Structural analysis of the human BIN1 gene. Evidence for tissue-specific transcriptional regulation and alternate RNA splicing." in: The Journal of biological chemistry, Vol. 272, Issue 50, pp. 31453-8, (1998) (PubMed).
Aliases for BIN1 抗体
bridging integrator 1 (BIN1) 抗体bridging integrator 1 S homeolog (bin1.S) 抗体
bridging integrator 1 (bin1) 抗体
bridging integrator 1b (bin1b) 抗体
bridging integrator 1 (Bin1) 抗体
ALP-1 抗体
amph2 抗体
AMPH2 抗体
amphl 抗体
AMPHL 抗体
Amphl 抗体
bin1 抗体
BIN1 抗体
BRAMP-2 抗体
cb57 抗体
MGC53185 抗体
MGC76187 抗体
sh3p9 抗体
SH3P9 抗体
zgc:86701 抗体
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