beta Amyloid 产品
(Amyloid beta (Abeta))
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This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured beta Amyloid Categories
beta Amyloid 抗体
High quality antibodies with extensive validation data.
beta Amyloid ELISA试剂盒
Reliable ELISA kits for a wide range of species.
beta Amyloid 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended beta Amyloid 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF
Validations
- (4)
- (4)
- (2)
Cat. No.
ABIN5508784
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC
Validations
- (1)
- (7)
- (2)
Cat. No.
ABIN95037
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, IHC (p)
Validations
- (3)
Cat. No.
ABIN2888562
Quantity
100 μL
Datasheet
Datasheet
Recommended beta Amyloid ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative
Validations
- (1)
Cat. No.
ABIN1882410
Quantity
1 kit
Datasheet
Datasheet
Reactivity
Mouse, Rat
Analytical Method
Quantitative
Validations
- (1)
Cat. No.
ABIN1882413
Quantity
1 kit
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN2708079
Quantity
96 tests
Datasheet
Datasheet
Recommended beta Amyloid 蛋白
Latest Publications for our beta Amyloid Products
: "Tanshinone IIA ameliorates cognitive deficits by inhibiting endoplasmic reticulum stress-induced apoptosis in APP/PS1 transgenic mice." in: Neurochemistry international, Vol. 133, pp. 104610, (2020) (PubMed).: "Systemic LPS-induced Aβ-solubilization and clearance in AβPP-transgenic mice is diminished by heparanase overexpression." in: Scientific reports, Vol. 9, Issue 1, pp. 4600, (2020) (PubMed).
: "Heterochromatic genome instability and neurodegeneration sharing similarities with Alzheimer's disease in old Bmi1+/- mice." in: Scientific reports, Vol. 9, Issue 1, pp. 594, (2019) (PubMed).
: "Repeat propofol anesthesia does not exacerbate plaque deposition or synapse loss in APP/PS1 Alzheimer's disease mice." in: BMC anesthesiology, Vol. 18, Issue 1, pp. 47, (2019) (PubMed).
: "Neutralization of IL-17 rescues amyloid-β-induced neuroinflammation and memory impairment." in: British journal of pharmacology, (2019) (PubMed).
: "Age moderates the effects of traumatic brain injury on beta-amyloid plaque load in APP/PS1 mice." in: Journal of neurotrauma, (2019) (PubMed).
: "Effect of growth differentiation factor-15 secreted by human umbilical cord blood-derived mesenchymal stem cells on amyloid beta levels in in vitro and in vivo models of Alzheimer's disease." in: Biochemical and biophysical research communications, Vol. 504, Issue 4, pp. 933-940, (2019) (PubMed).
: "K284-6111 prevents the amyloid beta-induced neuroinflammation and impairment of recognition memory through inhibition of NF-κB-mediated CHI3L1 expression." in: Journal of neuroinflammation, Vol. 15, Issue 1, pp. 224, (2019) (PubMed).
: "Erythrocytic α-Synuclein as a potential biomarker for Parkinson's disease." in: Translational neurodegeneration, Vol. 8, pp. 15, (2019) (PubMed).
: "Impact of TREM2 risk variants on brain region-specific immune activation and plaque microenvironment in Alzheimer's disease patient brain samples." in: Acta neuropathologica, (2019) (PubMed).
Synonyms and alternative names related to beta Amyloid
amyloid beta precursor protein (APP), amyloid beta precursor protein (app), amyloid beta precursor protein (App), amyloid beta (A4) precursor protein (App), AAA, aaa, ABETA, abeta, Abeta, ABPP, abpp, Abpp, AD1, ad1, Adap, Ag, APPI, appi, betaApp, CTFgamma, ctfgamma, CVAP, cvap, Cvap, E030013M08Rik, PN-II, PN2, pn2Protein level used designations for beta Amyloid
- alzheimer disease amyloid protein
- amyloid beta A4 protein
- beta-amyloid peptide
- cerebral vascular amyloid peptide
- peptidase nexin-II
- preA4
- protease nexin-II
- amyloid beta (A4) precursor protein (peptidase nexin-2, Alzheimer disease)
- amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease)
- beta-amyloid precursor protein
- alzheimer disease amyloid A4 protein homolog
- amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease)
- ABPP
- AG
- amyloid A4
- amyloidogenic glycoprotein
- appican
- protease nexin II
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