BCR 抗体
(Breakpoint Cluster Region (BCR))
A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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BCR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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Find BCR 抗体 for a variety of species such as anti-Human BCR, anti-Mouse BCR, anti-Rat BCR. The species listed below are among those available. Click on a link to go to the corresponding products.
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Find available monoclonal or polyclonal BCR 抗体. Click on a link to go to the corresponding products.
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Popular BCR 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, PLA
Validations
- (5)
Cat. No.
ABIN513693
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS
Validations
- (5)
Cat. No.
ABIN5611129
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (4)
Cat. No.
ABIN6256715
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IF, ICC
Validations
- (3)
Cat. No.
ABIN6256655
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (3)
Cat. No.
ABIN6137518
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, PLA
Validations
- (2)
Cat. No.
ABIN513692
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IF, ICC
Validations
- (2)
Cat. No.
ABIN6260240
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN1531493
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (1)
Cat. No.
ABIN683653
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7138990
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN3181935
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC
Validations
- (1)
Cat. No.
ABIN3183509
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN1327364
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
IF, IHC (p), IA
Validations
- (5)
Cat. No.
ABIN2192147
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ICC
Validations
- (2)
Cat. No.
ABIN5013247
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our BCR 抗体
: "Anti-inflammatory agents and monoHER protect against DOX-induced cardiotoxicity and accumulation of CML in mice." in: British journal of cancer, Vol. 96, Issue 6, pp. 937-43, (2007) (PubMed).: "Functioning of oxidative phosphorylation in liver mitochondria of high-fat diet fed rats." in: Biochimica et biophysica acta, Vol. 1772, Issue 3, pp. 307-16, (2007) (PubMed).
: "N(epsilon)-(carboxymethyl)lysine depositions in intramyocardial blood vessels in human and rat acute myocardial infarction: a predictor or reflection of infarction?" in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 26, Issue 11, pp. 2497-503, (2006) (PubMed).
: "Argpyrimidine-modified Heat shock protein 27 in human non-small cell lung cancer: a possible mechanism for evasion of apoptosis." in: Cancer letters, Vol. 241, Issue 2, pp. 309-19, (2006) (PubMed).
: "Interferon consensus sequence binding protein (ICSBP; IRF-8) antagonizes BCR/ABL and down-regulates bcl-2." in: Blood, Vol. 103, Issue 9, pp. 3480-9, (2004) (PubMed).
: "p210BCR/ABL-induced alteration of pre-mRNA splicing in primary human CD34+ hematopoietic progenitor cells." in: Leukemia, Vol. 18, Issue 4, pp. 727-33, (2004) (PubMed).
: "A direct binding site for Grb2 contributes to transformation and leukemogenesis by the Tel-Abl (ETV6-Abl) tyrosine kinase." in: Molecular and cellular biology, Vol. 24, Issue 11, pp. 4685-95, (2004) (PubMed).
: "Identification of genes differentially regulated by the P210 BCR/ABL1 fusion oncogene using cDNA microarrays." in: Experimental hematology, Vol. 32, Issue 5, pp. 476-82, (2004) (PubMed).
: "More fibrosis and thrombotic complications but similar expression patterns of markers for coagulation and inflammation in symptomatic plaques from DM2 patients." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 52, Issue 9, pp. 1141-9, (2004) (PubMed).
: "Tyrosine phosphorylation of Grb2 by Bcr/Abl and epidermal growth factor receptor: a novel regulatory mechanism for tyrosine kinase signaling." in: The EMBO journal, Vol. 20, Issue 23, pp. 6793-804, (2001) (PubMed).
Aliases for BCR 抗体
breakpoint cluster region (bcr) 抗体BCR, RhoGEF and GTPase activating protein (BCR) 抗体
BCR, RhoGEF and GTPase activating protein (bcr) 抗体
breakpoint cluster region (Bcr) 抗体
BCR, RhoGEF and GTPase activating protein (Bcr) 抗体
5133400C09Rik 抗体
AI561783 抗体
AI853148 抗体
ALL 抗体
BCR 抗体
BCR1 抗体
CML 抗体
D22S11 抗体
D22S662 抗体
mKIAA3017 抗体
PHL 抗体
si:dkey-83d9.7 抗体
zK83D9.7 抗体
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