BCMA 产品
(Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))
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The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008].
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Featured BCMA Categories
BCMA 抗体
High quality antibodies with extensive validation data.
BCMA ELISA试剂盒
Reliable ELISA kits for a wide range of species.
BCMA 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
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Recommended BCMA ELISA试剂盒
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Latest Publications for our BCMA Products
: "Hypoxia Selectively Impairs CAR-T Cells In Vitro." in: Cancers, Vol. 11, Issue 5, (2019) (PubMed).: "Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells." in: Haematologica, (2019) (PubMed).
: "Anti-CD19 CAR T cells with high-dose melphalan and autologous stem cell transplantation for refractory multiple myeloma. ..." in: JCI insight, Vol. 3, Issue 8, (2018) (PubMed).
: "Pre-clinical validation of B cell maturation antigen (BCMA) as a target for T cell immunotherapy of multiple myeloma." in: Oncotarget, Vol. 9, Issue 40, pp. 25764-25780, (2018) (PubMed).
: "CAR-T Cells Based on Novel BCMA Monoclonal Antibody Block Multiple Myeloma Cell Growth." in: Cancers, Vol. 10, Issue 9, (2018) (PubMed).
: "Clinical relevance of circulating anti-ENA and anti-dsDNA secreting cells from SLE patients and their dependence on STAT-3 activation." in: European journal of immunology, Vol. 47, Issue 7, pp. 1211-1219, (2017) (PubMed).
: "The BAFF receptor TACI controls IL-10 production by regulatory B cells and CLL B cells." in: Leukemia, Vol. 30, Issue 1, pp. 163-72, (2016) (PubMed).
: "γ-Secretase directly sheds the survival receptor BCMA from plasma cells." in: Nature communications, Vol. 6, pp. 7333, (2015) (PubMed).
: "The immunoregulator soluble TACI is released by ADAM10 and reflects B cell activation in autoimmunity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 2, pp. 542-52, (2015) (PubMed).
: "PD-L1hi B cells are critical regulators of humoral immunity." in: Nature communications, Vol. 6, pp. 5997, (2015) (PubMed).
Synonyms and alternative names related to BCMA
TNF receptor superfamily member 17 (Tnfrsf17), TNF receptor superfamily member 17 (TNFRSF17), tumor necrosis factor receptor superfamily, member 17 (Tnfrsf17), BCM, BCMA, CD269, Tnfrsf13, TNFRSF13A, Tnfrsf13a, TNFRSF17Protein level used designations for BCMA
- tumor necrosis factor receptor superfamily member 17
- tumor necrosis factor receptor superfamily, member 17
- B cell maturation antigen
- B-cell maturation factor
- B-cell maturation protein
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