BCL11A 抗体
(B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))
This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
recommended
BCL11A 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 3D9 unconjugated
recommended
BCL11A 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 斑马鱼, 小鸡, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
recommended
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Popular BCL11A 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IF
Validations
- (5)
Cat. No.
ABIN526947
Quantity
100 μg
Datasheet
Datasheet
Application
WB, IHC, IHC (p)
Validations
- (4)
Cat. No.
ABIN6741578
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7145171
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IP
Validations
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Cat. No.
ABIN526945
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN790476
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Cow, Dog, Horse, Human, Mouse, Pig, Rat, Zebrafish (Danio rerio)
Application
WB, IHC
Validations
- (1)
- (2)
Cat. No.
ABIN2781048
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, IP, ICC
Validations
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Cat. No.
ABIN7441184
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN565690
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN1989540
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ICC, IF
Validations
- (1)
Cat. No.
ABIN6971429
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Bat, Chicken, Cow, Dog, Guinea Pig, Human, Monkey, Mouse, Pig, Rabbit, Rat, Xenopus laevis, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
Cat. No.
ABIN6746172
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Chicken, Cow, Dog, Human, Mouse, Rat, Xenopus laevis, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
Cat. No.
ABIN927793
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN3028488
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), EIA
Validations
- (2)
Cat. No.
ABIN782364
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN1387845
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our BCL11A 抗体
: "A natural regulatory mutation in the proximal promoter elevates fetal globin expression by creating a de novo GATA1 site." in: Blood, Vol. 133, Issue 8, pp. 852-856, (2019) (PubMed).: "Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding." in: Nature genetics, Vol. 50, Issue 4, pp. 498-503, (2018) (PubMed).
: "Bcl11a controls Flt3 expression in early hematopoietic progenitors and is required for pDC development in vivo." in: PLoS ONE, Vol. 8, Issue 5, pp. e64800, (2013) (PubMed).
: "Transcriptional silencing of {gamma}-globin by BCL11A involves long-range interactions and cooperation with SOX6." in: Genes & development, Vol. 24, Issue 8, pp. 783-98, (2010) (PubMed).
: "BCL11A represses HBG transcription in K562 cells." in: Blood cells, molecules & diseases, Vol. 42, Issue 2, pp. 144-9, (2009) (PubMed).
: "Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 5, pp. 1620-5, (2008) (PubMed).
: "Novel markers of normal and neoplastic human plasmacytoid dendritic cells." in: Blood, Vol. 111, Issue 7, pp. 3778-92, (2008) (PubMed).
: "Functional studies of BCL11A: characterization of the conserved BCL11A-XL splice variant and its interaction with BCL6 in nuclear paraspeckles of germinal center B cells." in: Molecular cancer, Vol. 5, pp. 18, (2006) (PubMed).
: "The BCL11AXL transcription factor: its distribution in normal and malignant tissues and use as a marker for plasmacytoid dendritic cells." in: Leukemia, Vol. 20, Issue 8, pp. 1439-41, (2006) (PubMed).
: "Hydroxyurea differentially modulates activator and repressors of γ-globin gene in erythroblasts of responsive and non-responsive patients with sickle cell disease in correlation with Index of ..." in: Haematologica, Vol. 102, Issue 12, pp. 1995-2004 (PubMed).
Aliases for BCL11A 抗体
B cell CLL/lymphoma 11A (zinc finger protein) (Bcl11a) 抗体B-cell CLL/lymphoma 11A (BCL11A) 抗体
B-cell CLL/lymphoma 11A L homeolog (bcl11a.L) 抗体
B-cell CLL/lymphoma 11A (Bcl11a) 抗体
B-cell CLL/lymphoma 11Aa (bcl11aa) 抗体
2810047E18Rik 抗体
BCL-11A 抗体
bcl11a 抗体
BCL11A-L 抗体
BCL11a-M 抗体
BCL11A-S 抗体
BCL11A-XL 抗体
Ctip1 抗体
CTIP1 抗体
D930021L15Rik 抗体
Evi9 抗体
EVI9 抗体
Evi9a 抗体
Evi9b 抗体
Evi9c 抗体
HBFQTL5 抗体
mKIAA1809 抗体
wu:fi09f10 抗体
zgc:136898 抗体
ZNF856 抗体
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