BCCIP 抗体
(BRCA2 and CDKN1A Interacting Protein (BCCIP))
This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
recommended
recommended
recommended
BCCIP 抗体 by 适用
Find BCCIP 抗体 for a variety of species such as anti-Human BCCIP, anti-Mouse BCCIP, anti-Rat BCCIP. The species listed below are among those available. Click on a link to go to the corresponding products.
BCCIP 抗体 by 应用范围
Find BCCIP 抗体 validated for a specific application such as WB, IF (p), IF (cc), IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.
BCCIP 抗体 by 抗体来源
Find BCCIP 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
BCCIP 抗体 by 抗原表位
Find BCCIP 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.
BCCIP 抗体 by 克隆形成能力
Find available monoclonal or polyclonal BCCIP 抗体. Click on a link to go to the corresponding products.
Popular BCCIP 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (4)
Cat. No.
ABIN6137485
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (4)
Cat. No.
ABIN2856892
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN527937
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (2)
Cat. No.
ABIN527936
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, ICC
Validations
- (2)
Cat. No.
ABIN6260217
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN566032
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC
Validations
- (1)
Cat. No.
ABIN7264637
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF (p), IF (cc), IHC (p), IHC (fro)
Validations
Cat. No.
ABIN872717
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN884609
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IF (p), IF (cc)
Validations
Cat. No.
ABIN2810207
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IF (p), IF (cc)
Validations
Cat. No.
ABIN884596
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IF (p), IF (cc)
Validations
Cat. No.
ABIN884597
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IF (p), IF (cc)
Validations
Cat. No.
ABIN884598
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IF (p), IF (cc)
Validations
Cat. No.
ABIN884608
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IF (p), IF (cc)
Validations
Cat. No.
ABIN4997246
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our BCCIP 抗体
: "The BRCA2-interacting protein BCCIP functions in RAD51 and BRCA2 focus formation and homologous recombinational repair." in: Molecular and cellular biology, Vol. 25, Issue 5, pp. 1949-57, (2005) (PubMed).: "Inhibition of G1 to S cell cycle progression by BCCIP beta." in: Cell cycle (Georgetown, Tex.), Vol. 3, Issue 3, pp. 343-8, (2004) (PubMed).
: "Unique de novo mutation of BRCA2 in a woman with early onset breast cancer." in: Journal of medical genetics, Vol. 39, Issue 2, pp. 126-8, (2002) (PubMed).
: "Inhibition of breast and brain cancer cell growth by BCCIPalpha, an evolutionarily conserved nuclear protein that interacts with BRCA2." in: Oncogene, Vol. 20, Issue 3, pp. 336-45, (2001) (PubMed).
: "TOK-1, a novel p21Cip1-binding protein that cooperatively enhances p21-dependent inhibitory activity toward CDK2 kinase." in: The Journal of biological chemistry, Vol. 275, Issue 40, pp. 31145-54, (2000) (PubMed).
Aliases for BCCIP 抗体
BRCA2 and CDKN1A interacting protein (BCCIP) 抗体BRCA2 and CDKN1A interacting protein (bccip) 抗体
BRCA2 and CDKN1A interacting protein L homeolog (bccip.L) 抗体
BRCA2 and CDKN1A interacting protein (Bccip) 抗体
1110013J05Rik 抗体
BCCIP 抗体
DKFZp459K2416 抗体
MGC82792 抗体
MGC89311 抗体
mp:zf637-1-000774 抗体
tok-1 抗体
TOK-1 抗体
TOK1 抗体
zgc:110272 抗体
您还需要查找其他产品吗？
You are here:
