BARD1 抗体
(BRCA1 Associated RING Domain 1 (BARD1))
This gene encodes a protein which interacts with the N-terminal region of BRCA1. In addition to its ability to bind BRCA1 in vivo and in vitro, it shares homology with the 2 most conserved regions of BRCA1: the N-terminal RING motif and the C-terminal BRCT domain. The RING motif is a cysteine-rich sequence found in a variety of proteins that regulate cell growth, including the products of tumor suppressor genes and dominant protooncogenes. This protein also contains 3 tandem ankyrin repeats. The BARD1/BRCA1 interaction is disrupted by tumorigenic amino acid substitutions in BRCA1, implying that the formation of a stable complex between these proteins may be an essential aspect of BRCA1 tumor suppression. This protein may be the target of oncogenic mutations in breast or ovarian cancer. [provided by RefSeq, Jul 2008].
recommended
BARD1 适用: 人 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
recommended
recommended
BARD1 抗体 by 适用
Find BARD1 抗体 for a variety of species such as anti-Human BARD1, anti-Mouse BARD1, anti-Rat BARD1. The species listed below are among those available. Click on a link to go to the corresponding products.
BARD1 抗体 by 抗体来源
Find BARD1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
BARD1 抗体 by 抗原表位
Find BARD1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.
BARD1 抗体 by 克隆形成能力
Find available monoclonal or polyclonal BARD1 抗体. Click on a link to go to the corresponding products.
BARD1 抗体 by 克隆
Find BARD1 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
Popular BARD1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (1)
- (1)
Cat. No.
ABIN706496
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF
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- (2)
Cat. No.
ABIN560033
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IHC
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Cat. No.
ABIN7188551
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
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Cat. No.
ABIN7184419
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA
Validations
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Cat. No.
ABIN7145762
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
WB
Validations
- (1)
Cat. No.
ABIN6137449
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP, DB
Validations
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Cat. No.
ABIN930988
Quantity
50 μg
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN706498
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, FACS, IF (cc), IF (p)
Validations
Cat. No.
ABIN884508
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IF (cc), IF (p)
Validations
Cat. No.
ABIN884509
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IF (cc), IF (p)
Validations
Cat. No.
ABIN2810177
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IF (cc), IF (p)
Validations
Cat. No.
ABIN4997194
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IF (cc), IF (p)
Validations
Cat. No.
ABIN4997195
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IF (cc), IF (p)
Validations
Cat. No.
ABIN884511
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IF (cc), IF (p)
Validations
Cat. No.
ABIN884512
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our BARD1 抗体
: "FOXK2 transcription factor suppresses ER?-positive breast cancer cell growth through down-regulating the stability of ER? via mechanism involving BRCA1/BARD1." in: Scientific reports, Vol. 5, pp. 8796, (2015) (PubMed).: "The BARD1 BRCT domain contributes to p53 binding, cytoplasmic and mitochondrial localization, and apoptotic function." in: Cellular signalling, Vol. 27, Issue 9, pp. 1763-71, (2015) (PubMed).
: "Prognostic and biological significance of proliferation and HER2 expression in the luminal class of breast cancer." in: Breast cancer research and treatment, Vol. 145, Issue 2, pp. 317-30, (2014) (PubMed).
: "SUMOylation proteins in breast cancer." in: Breast cancer research and treatment, Vol. 144, Issue 3, pp. 519-30, (2014) (PubMed).
: "Common variation at BARD1 results in the expression of an oncogenic isoform that influences neuroblastoma susceptibility and oncogenicity. ..." in: Cancer research, Vol. 72, Issue 8, pp. 2068-78, (2012) (PubMed).
: "The in vivo dynamic organization of BRCA1-A complex proteins at DNA damage-induced nuclear foci." in: Traffic (Copenhagen, Denmark), Vol. 13, Issue 6, pp. 800-14, (2012) (PubMed).
: "Expression of oncogenic BARD1 isoforms affects colon cancer progression and correlates with clinical outcome." in: British journal of cancer, Vol. 107, Issue 4, pp. 675-83, (2012) (PubMed).
: "BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair." in: Journal of cell science, Vol. 125, Issue Pt 15, pp. 3529-34, (2012) (PubMed).
: "HERC2 is an E3 ligase that targets BRCA1 for degradation." in: Cancer research, Vol. 70, Issue 15, pp. 6384-92, (2010) (PubMed).
: "Altered expression of anti-apoptotic proteins in non-involved tissue from cancer-containing breasts." in: Breast cancer research and treatment, Vol. 114, Issue 1, pp. 63-9, (2009) (PubMed).
Aliases for BARD1 抗体
BRCA1 associated RING domain 1 (BARD1) 抗体BRCA1 associated RING domain 1 (bard1) 抗体
BRCA1 associated RING domain 1 (Bard1) 抗体
BARD1 抗体
ENSMUSG00000060893 抗体
ENSMUSG00000073653 抗体
LOC100147913 抗体
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