BANF1 产品
(Barrier To Autointegration Factor 1 (BANF1))
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The protein encoded by this gene was first identified by its ability to protect retroviruses from intramolecular integration and therefore promote intermolecular integration into the host cell genome. The protein forms a homodimer which localizes to both the nucleus and cytoplasm and is specifically associated with chromosomes during mitosis. This protein binds to double stranded DNA in a non-specific manner and also binds to LEM-domain containing proteins of the nuclear envelope. This protein is thought to facilitate nuclear reassembly by binding with both DNA and inner nuclear membrane proteins and thereby recruit chromatin to the nuclear periphery. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Jan 2009].
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Latest Publications for our BANF1 Products
: "Transcription upregulation via force-induced direct stretching of chromatin." in: Nature materials, Vol. 15, Issue 12, pp. 1287-1296, (2016) (PubMed).: "Depletion of autophagy receptor p62/SQSTM1 enhances the efficiency of gene delivery in mammalian cells." in: FEBS letters, Vol. 590, Issue 16, pp. 2671-80, (2016) (PubMed).
: "Dephosphorylation of barrier-to-autointegration factor by protein phosphatase 4 and its role in cell mitosis." in: The Journal of biological chemistry, Vol. 289, Issue 2, pp. 1119-27, (2014) (PubMed).
: "Functional disruption of the moloney murine leukemia virus preintegration complex by vaccinia-related kinases." in: The Journal of biological chemistry, Vol. 285, Issue 31, pp. 24032-43, (2010) (PubMed).
: "Solution structure of the constant region of nuclear envelope protein LAP2 reveals two LEM-domain structures: one binds BAF and the other binds DNA." in: The EMBO journal, Vol. 20, Issue 16, pp. 4399-407, (2001) (PubMed).
: "LAP2 binding protein 1 (L2BP1/BAF) is a candidate mediator of LAP2-chromatin interaction." in: Journal of cell science, Vol. 112 ( Pt 15), pp. 2485-92, (1999) (PubMed).
: "The barrier-to-autointegration protein is a host factor for HIV type 1 integration." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 26, pp. 15270-4, (1999) (PubMed).
Synonyms and alternative names related to BANF1
barrier to autointegration factor 1 (BANF1), barrier to autointegration factor 1 (Banf1), barrier to autointegration factor 1 (banf1), barrier to autointegration factor 1 pseudogene (LOC100397017), barrier to autointegration factor (baf), barrier to autointegration factor 1 S homeolog (banf1.S), anon-WO0172774.178, BAF, Baf, baf, BANF1, banf1, banf1-a, banf1-b, BCRP1, Bcrp1, bcrp1, C78287, CG7380, D14S1460, dBAF, DKFZp468C097, Dmel\\CG7380, fa01c01, L2bp1, L2bp1/Baf, NGPS, wu:fa01c01, zgc:77767Protein level used designations for BANF1
- barrier-to-autointegration factor
- breakpoint cluster region protein 1
- Breakpoint cluster region protein, uterine leiomyoma, 1
- Breakpoint cluster region protein, uterine leiomyoma, 1; barrier to autointegration factor
- LAP2-binding protein 1
- Lap2 binding protein 1
- barrier to autointegration factor 1
- Barrier-to-autointegration factor
- LAP2 binding protein 1
- CG7380-PA
- CG7380-PB
- baf-PA
- baf-PB
- barrier-to-autointegration factor B
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