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BAK1 产品

(BCL2-Antagonist/killer 1 (BAK1))

Categories

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008].

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Featured BAK1 Categories

BAK1 抗体

High quality antibodies with extensive validation data.

BAK1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

BAK1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended BAK1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (8)
Cat. No. ABIN3020677
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, FACS, ICC, Neut
Validations
  • (6)
Cat. No. ABIN5611250
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (2)
  • (10)
Cat. No. ABIN3042342
Quantity 100 μg
Datasheet Datasheet

Recommended BAK1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965129
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965130
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954055
Quantity 96 tests
Datasheet Datasheet

Recommended BAK1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1346390
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1346392
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7396205
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our BAK1 Products

Yu, Li, Chen, Lai, Lin, Korla, Chai, Ko, Chen, Hwang, Lee, Sheu: "YWHAZ amplification/overexpression defines aggressive bladder cancer and contributes to chemo-/radio-resistance by suppressing caspase-mediated apoptosis." in: The Journal of pathology, (2019) (PubMed).

Yang, Pei, Zhang, Liao, Yu, Qiao, Han, Li, Hu, Guo, Pan, Tang: "Copper induces oxidative stress and apoptosis through mitochondria-mediated pathway in chicken hepatocytes." in: Toxicology in vitro : an international journal published in association with BIBRA, Vol. 54, pp. 310-316, (2019) (PubMed).

Huang, Li, Pang, Chen, Xiang, Feng, Su, Li, Zhang, Liu: "MicroRNA-29c Correlates with Neuroprotection Induced by FNS by Targeting Both Birc2 and Bak1 in Rat Brain after Stroke." in: CNS neuroscience & therapeutics, Vol. 21, Issue 6, pp. 496-503, (2016) (PubMed).

Huang, Chao, Lee, Lu, Cheng, Yang, Wang, Chang, Huang: "Paraquat Induces Cell Death Through Impairing Mitochondrial Membrane Permeability." in: Molecular neurobiology, (2015) (PubMed).

Bamodu, Huang, Tzeng, Wu, Wang, Yeh, Chao: "Ovatodiolide sensitizes aggressive breast cancer cells to doxorubicin, eliminates their cancer stem cell-like phenotype, and reduces doxorubicin-associated toxicity." in: Cancer letters, Vol. 364, Issue 2, pp. 125-34, (2015) (PubMed).

Naik, MacFarlane, Sarin: "Notch4 Signaling Confers Susceptibility to TRAIL-Induced Apoptosis in Breast Cancer Cells." in: Journal of cellular biochemistry, Vol. 116, Issue 7, pp. 1371-80, (2015) (PubMed).

Zhu, Wang, Liang, Wang, Zhang, Li, Ying: "Regulation of cell transformation by Rb-controlled redox homeostasis." in: PLoS ONE, Vol. 9, Issue 7, pp. e102582, (2014) (PubMed).

Garg, Ramdas, Vijayalakshmi, Shivashankar, Sarin: "The C-terminal domain (CTD) in linker histones antagonizes anti-apoptotic proteins to modulate apoptotic outcomes at the mitochondrion." in: Cell death & disease, Vol. 5, pp. e1058, (2014) (PubMed).

Lindner, Concannon, Boukes, Cannon, Llambi, Ryan, Boland, Kehoe, McNamara, Murray, Kay, Hector, Green, Huber, Prehn: "Systems analysis of BCL2 protein family interactions establishes a model to predict responses to chemotherapy." in: Cancer research, Vol. 73, Issue 2, pp. 519-28, (2013) (PubMed).

Plötz, Gillissen, Hossini, Daniel, Eberle: "Disruption of the VDAC2-Bak interaction by Bcl-x(S) mediates efficient induction of apoptosis in melanoma cells." in: Cell death and differentiation, Vol. 19, Issue 12, pp. 1928-38, (2012) (PubMed).

Synonyms and alternative names related to BAK1

BCL2 antagonist/killer 1 (BAK1), BCL2-antagonist/killer 1 (Bak1), BCL2 antagonist/killer 1 (Bak1), BCL2 antagonist/killer 1 L homeolog (bak1.L), BAK, Bak, bak, BAK-LIKE, Bak1, bak1, BCL2L7, CDN1, N-Bak, N-BAK1

Protein level used designations for BAK1

  • BCL2-like 7 protein
  • apoptosis regulator BAK
  • bcl-2 homologous antagonist/killer
  • bcl-2-like protein 7
  • bcl2-L-7
  • pro-apoptotic protein BAK
  • Bcl2 homologous antagonist/killer
  • Bcl-2-like 7
  • BCL2 antagonist/killer 1 L homeolog
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