BAI1 产品
(Brain-Specific Angiogenesis Inhibitor 1 (BAI1))
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Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas [provided by RefSeq, Jul 2008].
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BAI1 抗体
High quality antibodies with extensive validation data.
BAI1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
BAI1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
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Cat. No.
ABIN6257957
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ABIN3181614
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Recommended BAI1 ELISA试剂盒
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Latest Publications for our BAI1 Products
: "BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation." in: Cancer cell, Vol. 33, Issue 6, pp. 1004-1016.e5, (2018) (PubMed).: "Phosphatidylserine receptor BAI1 and apoptotic cells as new promoters of myoblast fusion." in: Nature, Vol. 497, Issue 7448, pp. 263-7, (2013) (PubMed).
: "Antiangiogenic activity of BAI1 in vivo: implications for gene therapy of human glioblastomas." in: Cancer gene therapy, Vol. 13, Issue 4, pp. 385-92, (2006) (PubMed).
: "Brain angiogenesis inhibitor 1 is differentially expressed in normal brain and glioblastoma independently of p53 expression." in: The American journal of pathology, Vol. 162, Issue 1, pp. 19-27, (2002) (PubMed).
: "Overexpression of the p53-inducible brain-specific angiogenesis inhibitor 1 suppresses efficiently tumour angiogenesis." in: British journal of cancer, Vol. 86, Issue 3, pp. 490-6, (2002) (PubMed).
: "Brain-specific angiogenesis inhibitor 1 (BAI1) is expressed in human cerebral neuronal cells." in: Neuroscience research, Vol. 43, Issue 1, pp. 69-74, (2002) (PubMed).
Synonyms and alternative names related to BAI1
brain-specific angiogenesis inhibitor 1 (BAI1), adhesion G protein-coupled receptor B1 (ADGRB1), brain-specific angiogenesis inhibitor 1 (LOC100228084), adhesion G protein-coupled receptor B1 (Adgrb1), B830018M07Rik, BAI1, GDAIF, mKIAA4089, R75078Protein level used designations for BAI1
- brain-specific angiogenesis inhibitor 1
- brain-specific angiogenesis inhibitor 1-like
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