AUH 产品
(AU RNA Binding Protein/enoyl-CoA Hydratase (AUH))
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The methylglutaconyl-CoA hydratase, mitochondrial protein binds to the AU-rich element (ARE), a common element found in the 3' UTR of rapidly decaying mRNA such as c-fos, c-myc and granulocyte/ macrophage colony stimulating factor. ARE elements are involved in directing RNA to rapid degradation and deadenylation. AUH is also homologous to enol-CoA hydratase, an enzyme involved in fatty acid degradation, and has been shown to have intrinsic hydratase enzymatic activity. AUH is thus a bifunctional chimera between RNA binding and metabolic enzyme activity. A possible subcellular localization in the mitochondria has been demonstrated for the mouse homolog of this protein which shares 92% identity with the human protein. It has been suggested that AUH may have a novel role as a mitochondrial located AU-binding protein. Human AUH is expressed as a single mRNA species of 1.8 kb, and translated as a 40-kDa precursor protein which is subsequently processed to a 32-kDa mature form. [provided by RefSeq, May 2010].
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Featured AUH Categories
AUH 抗体
High quality antibodies with extensive validation data.
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Reliable ELISA kits for a wide range of species.
AUH 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
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Latest Publications for our AUH Products
: "The von Hippel-Lindau gene product inhibits renal cell apoptosis via Bcl-2-dependent pathways." in: The Journal of biological chemistry, Vol. 276, Issue 44, pp. 40599-605, (2001) (PubMed).: "An essential role for Bruton's [corrected] tyrosine kinase in the regulation of B-cell apoptosis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 20, pp. 10966-71, (1996) (PubMed).
Synonyms and alternative names related to AUH
AU RNA binding methylglutaconyl-CoA hydratase (AUH), AU RNA binding protein/enoyl-coenzyme A hydratase (Auh), AU RNA binding methylglutaconyl-CoA hydratase (Auh), AU RNA binding protein/enoyl-CoA hydratase (auh), AU RNA binding protein/enoyl-CoA hydratase S homeolog (auh.S), C77140, W91705, wu:fb81b10, zgc:101057Protein level used designations for AUH
- 3-methylglutaconyl-CoA hydratase
- AU RNA binding protein/enoyl-Coenzyme A hydratase
- AU RNA-binding protein/enoyl-Coenzyme A hydratase
- AU-binding protein/Enoyl-CoA hydratase
- AU-specific RNA-binding enoyl-CoA hydratase
- methylglutaconyl-CoA hydratase, mitochondrial
- AU-binding enoyl-CoA hydratase
- muAUH
- AU RNA binding protein/enoyl-coenzyme A hydratase
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