ATR 抗体
(ATR serine/threonine kinase (ATR))
The protein encoded by this gene belongs the PI3/PI4-kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1, checkpoint proteins RAD17, and RAD9, as well as tumor suppressor protein BRCA1. Mutations of this gene are associated with Seckel syndrome. An alternatively spliced transcript variant of this gene has been reported, however, its full length nature is not known. Transcript variants utilizing alternative polyA sites exist. [provided by RefSeq, Jul 2008].
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ATR 抗体 by 适用
Find ATR 抗体 for a variety of species such as anti-Human ATR, anti-Mouse ATR, anti-Rat ATR. The species listed below are among those available. Click on a link to go to the corresponding products.
ATR 抗体 by 应用范围
Find ATR 抗体 validated for a specific application such as ELISA, WB, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.
ATR 抗体 by 抗体来源
Find ATR 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
ATR 抗体 by 克隆形成能力
Find available monoclonal or polyclonal ATR 抗体. Click on a link to go to the corresponding products.
ATR 抗体 by 克隆
Find ATR 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
ATR 抗体 by 标记
Find ATR 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
Popular ATR 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC, WB
Validations
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Cat. No.
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Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
ELISA, FACS
Validations
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Cat. No.
ABIN7193431
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
ELISA, WB, IF
Validations
- (3)
Cat. No.
ABIN560011
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
ELISA, IHC, IHC (p)
Validations
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Cat. No.
ABIN574213
Quantity
50 μg
Datasheet
Datasheet
Reactivity
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Application
ELISA, IHC, WB
Validations
- (2)
Cat. No.
ABIN7169011
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, IHC, WB
Validations
- (2)
Cat. No.
ABIN6255330
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
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Cat. No.
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Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
ELISA, IHC
Validations
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Cat. No.
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Quantity
200 μL
Datasheet
Datasheet
Reactivity
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Application
ELISA, WB
Validations
- (1)
Cat. No.
ABIN560010
Quantity
50 μL
Datasheet
Datasheet
Reactivity
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Application
ELISA, IHC, WB
Validations
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Cat. No.
ABIN3183446
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
ELISA, IHC (p)
Validations
- (1)
Cat. No.
ABIN513645
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
WB
Validations
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Cat. No.
ABIN6137357
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN6137358
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (1)
Cat. No.
ABIN233834
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF, IC
Validations
- (2)
Cat. No.
ABIN7307510
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our ATR 抗体
: "ZFP161 regulates replication fork stability and maintenance of genomic stability by recruiting the ATR/ATRIP complex." in: Nature communications, Vol. 10, Issue 1, pp. 5304, (2019) (PubMed).: "A type I IFN-dependent DNA damage response regulates the genetic program and inflammasome activation in macrophages." in: eLife, Vol. 6, (2017) (PubMed).
: "Poly(ADP-ribose) binding to Chk1 at stalled replication forks is required for S-phase checkpoint activation." in: Nature communications, Vol. 4, pp. 2993, (2013) (PubMed).
: "Constitutive turnover of phosphorylation at Thr-412 of human p57/coronin-1 regulates the interaction with actin." in: The Journal of biological chemistry, Vol. 287, Issue 51, pp. 42910-20, (2012) (PubMed).
: "Dysregulation of IRP1-mediated iron metabolism causes gamma ray-specific radioresistance in leukemia cells." in: PLoS ONE, Vol. 7, Issue 11, pp. e48841, (2012) (PubMed).
: "Nek1 kinase functions in DNA damage response and checkpoint control through a pathway independent of ATM and ATR." in: Cell cycle (Georgetown, Tex.), Vol. 10, Issue 4, pp. 655-63, (2011) (PubMed).
: "Hsp90 inhibitor-mediated disruption of chaperone association of ATR with hsp90 sensitizes cancer cells to DNA damage." in: Molecular cancer therapeutics, Vol. 10, Issue 7, pp. 1194-206, (2011) (PubMed).
: "ATR suppresses telomere fragility and recombination but is dispensable for elongation of short telomeres by telomerase." in: The Journal of cell biology, Vol. 188, Issue 5, pp. 639-52, (2010) (PubMed).
: "ATM- and ATR-mediated response to DNA damage induced by a novel camptothecin, ST1968." in: Cancer letters, Vol. 292, Issue 2, pp. 186-96, (2010) (PubMed).
: "Multiple DNA damage signaling and repair pathways deregulated by simian virus 40 large T antigen." in: Journal of virology, Vol. 84, Issue 16, pp. 8007-20, (2010) (PubMed).
Aliases for ATR 抗体
ATR serine/threonine kinase (ATR) 抗体ataxia telangiectasia and Rad3 related (ATR) 抗体
ataxia telangiectasia and Rad3 related (Atr) 抗体
ATR serine/threonine kinase (Atr) 抗体
FCTCS 抗体
FRP1 抗体
MEC1 抗体
SCKL 抗体
SCKL1 抗体
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