ATR 产品
(Ataxia Telangiectasia and Rad3 Related (ATR))
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The protein encoded by this gene belongs the PI3/PI4-kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1, checkpoint proteins RAD17, and RAD9, as well as tumor suppressor protein BRCA1. Mutations of this gene are associated with Seckel syndrome. An alternatively spliced transcript variant of this gene has been reported, however, its full length nature is not known. Transcript variants utilizing alternative polyA sites exist. [provided by RefSeq, Jul 2008].
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Featured ATR Categories
ATR 抗体
High quality antibodies with extensive validation data.
Recommended ATR 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IP, ICC, IHC
Validations
- (2)
Cat. No.
ABIN7443059
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP, ICC, IHC (p), IF
Validations
Cat. No.
ABIN7467986
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP, ICC, IF, Func
Validations
Cat. No.
ABIN7467985
Quantity
100 μL
Datasheet
Datasheet
Recommended ATR ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6201396
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN6199496
Quantity
96 tests
Datasheet
Datasheet
Recommended ATR 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7416034
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our ATR Products
: "Phosphoinositide 3-kinase signalling pathways." in: Journal of cell science, Vol. 114, Issue Pt 8, pp. 1439-45, (2001) (PubMed).: "Oncogenic kinase signalling." in: Nature, Vol. 411, Issue 6835, pp. 355-65, (2001) (PubMed).
: "The RET proto-oncogene in human cancers." in: Oncogene, Vol. 19, Issue 49, pp. 5590-7, (2000) (PubMed).
Synonyms and alternative names related to ATR
ataxia telangiectasia and Rad3 related (Atr), ATR serine/threonine kinase (ATR), ataxia telangiectasia and Rad3 related (ATR), ATR serine/threonine kinase (atr), ATR serine/threonine kinase L homeolog (atr.L), Ataxia telangiectasia-mutated and RAD3-like protein (ATR), ARABIDOPSIS THALIANA ATAXIA TELANGIECTASIA-MUTATED AND RAD3-RELATED, ATATR, Ataxia telangiectasia-mutated and RAD3-related, ATR, ATRAD3, FCTCS, FRP1, frp1, MEC1, mec1, MHK7.5, MHK7_5, SCKL, sckl, SCKL1, sckl1, si:dkey-231j24.1, XATRProtein level used designations for ATR
- ataxia telangiectasia and Rad3 related
- ataxia telangiectasia and Rad3 related protein
- serine/threonine-protein kinase ATR-like
- FRAP-related protein 1
- FRAP-related protein-1
- MEC1, mitosis entry checkpoint 1, homolog
- Rad3 related protein
- ataxia telangiectasia and Rad3-related protein
- protein kinase ATR
- serine/threonine-protein kinase ATR
- checkpoint kinase
- protein kinase
- serine/threonine-protein kinase atr
您还需要查找其他产品吗？
- ATPOT1B
- ATPH1
- AtpG
- ATPFH
- ATPE
- ATPD
- ATPC1
- ATPBD4
- ATPBD3
- ATPase, Na+/K+ Transporting, beta 3 Polypeptide
- ATPase, Na+/K+ Transporting, alpha 3 Polypeptide
- ATPase, H+ Transporting, Lysosomal V0 Subunit A1
- ATPase, H+ Transporting, Lysosomal 16kDa, V0 Subunit C
- ATPase, Aminophospholipid Transporter, Class I, Type 8B, Member 2
- ATPase Inhibitory Factor 1
- ATPase Family, AAA Domain Containing 5
- ATPase expression protein 1, mitochondrial
- ATPase (Na/K)
- ATPase
- Atpalpha
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