ATP6V1C1 产品
(ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C1 (ATP6V1C1))
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This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene is one of two genes that encode the V1 domain C subunit proteins and is found ubiquitously. This C subunit is analogous but not homologous to gamma subunit of F-ATPases. Previously, this gene was designated ATP6D. [provided by RefSeq, Jul 2008].
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Featured ATP6V1C1 Categories
ATP6V1C1 抗体
High quality antibodies with extensive validation data.
ATP6V1C1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ATP6V1C1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7175232
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7247105
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN560005
Quantity
50 μL
Datasheet
Datasheet
Recommended ATP6V1C1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6209376
Quantity
96 tests
Datasheet
Datasheet
Recommended ATP6V1C1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346121
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346123
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2715057
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our ATP6V1C1 Products
: "V-ATPase: a master effector of E2F1-mediated lysosomal trafficking, mTORC1 activation and autophagy." in: Oncotarget, Vol. 6, Issue 29, pp. 28057-70, (2015) (PubMed).: "Structural and functional characterization of two human V-ATPase subunit gene promoters." in: Biochimica et biophysica acta, Vol. 1628, Issue 2, pp. 97-104, (2003) (PubMed).
: "Revised nomenclature for mammalian vacuolar-type H+ -ATPase subunit genes." in: Molecular cell, Vol. 12, Issue 4, pp. 801-3, (2003) (PubMed).
: "Neurotransmitter release: the dark side of the vacuolar-H+ATPase." in: Biology of the cell / under the auspices of the European Cell Biology Organization, Vol. 95, Issue 7, pp. 453-7, (2003) (PubMed).
Synonyms and alternative names related to ATP6V1C1
ATPase H+ transporting V1 subunit C1 (ATP6V1C1), ATPase, H+ transporting, lysosomal V1 subunit C1 (Atp6v1c1), ATPase H+ transporting V1 subunit C1 (Atp6v1c1), ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 (atp6v1c1), ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 L homeolog (atp6v1c1.L), ATPase, H+ transporting, lysosomal, V1 subunit C1a (atp6v1c1a), ATPase, H+ transporting, lysosomal, V1 subunit C1b (atp6v1c1b), 1700025B18Rik, ATP6C, ATP6D, atp6v1c1, atp6v1c1l, ATPase, si:zc215i13.2, U13839, VATC, vatC, Vma5, wu:fd12h05, zgc:92684Protein level used designations for ATP6V1C1
- H(+)-transporting two-sector ATPase, subunit C
- H+ -ATPase C subunit
- H+-transporting ATPase chain C, vacuolar
- V-ATPase C subunit
- V-ATPase subunit C 1
- V-type proton ATPase subunit C 1
- subunit C of vacuolar proton-ATPase V1 domain
- vacuolar ATP synthase subunit C
- vacuolar proton pump C subunit
- vacuolar proton pump subunit C 1
- vacuolar proton pump, 42-kD subunit
- vacuolar proton-ATPase, subunit C, VI domain
- ATPase, H+ transporting, V1 subunit C
- vacuolar H+ -ATPase C subunit
- ATPase, H+ transporting, lysosomal V1 subunit C1
- ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
- Vacuolar proton pump subunit C 1
- V-type proton ATPase subunit C 1-like
- ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C
- ATPase, H+ transporting, lysosomal, V1 subunit C
- V-ATPase subunit C 1-A
- V-type proton ATPase subunit C 1-A
- vacuolar proton pump subunit C 1-A
- ATPase, H+ transporting, lysosomal, V1 subunit C, isoform 1, like
- V-ATPase subunit C 1-B
- V-type proton ATPase subunit C 1-B
- vacuolar proton pump subunit C 1-B
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