ATP2B2 产品
(ATPase, Ca++ Transporting, Plasma Membrane 2 (ATP2B2))
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The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 2. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
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Featured ATP2B2 Categories
ATP2B2 抗体
High quality antibodies with extensive validation data.
ATP2B2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
ATP2B2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ATP2B2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse, Rat
Application
WB, ELISA, IF (p), IHC (fro), IHC (p), IF (cc)
Validations
- (1)
- (2)
Cat. No.
ABIN1385852
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7436264
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ELISA, IF
Validations
- (2)
Cat. No.
ABIN7163515
Quantity
100 μL
Datasheet
Datasheet
Recommended ATP2B2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6953996
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5674663
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN2850984
Quantity
96 tests
Datasheet
Datasheet
Recommended ATP2B2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7408519
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7398914
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3114272
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our ATP2B2 Products
: "Neuroplastin and Basigin Are Essential Auxiliary Subunits of Plasma Membrane Ca2+-ATPases and Key Regulators of Ca2+ Clearance." in: Neuron, Vol. 96, Issue 4, pp. 827-838.e9, (2017) (PubMed).: "Sphingomyelin-induced inhibition of the plasma membrane calcium ATPase causes neurodegeneration in type A Niemann-Pick disease." in: Molecular psychiatry, (2016) (PubMed).
: "Disrupted calcium homeostasis is involved in elevated zinc ion-induced photoreceptor cell death." in: Archives of biochemistry and biophysics, Vol. 560, pp. 44-51, (2014) (PubMed).
: "Zinc oxide nanoparticles decrease the expression and activity of plasma membrane calcium ATPase, disrupt the intracellular calcium homeostasis in rat retinal ganglion cells." in: The international journal of biochemistry & cell biology, Vol. 45, Issue 8, pp. 1849-59, (2013) (PubMed).
: "Plasma membrane Ca2+ pump in rat brain. Patterns of alternative splices seen by isoform-specific antibodies." in: The Journal of biological chemistry, Vol. 272, Issue 38, pp. 23741-7, (1997) (PubMed).
: "Cloning and expression of isoform 2 of the human plasma membrane Ca2+ ATPase. Functional properties of the enzyme and its splicing products." in: The Journal of biological chemistry, Vol. 269, Issue 42, pp. 26178-83, (1994) (PubMed).
: "Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes." in: The Journal of biological chemistry, Vol. 268, Issue 34, pp. 25993-6003, (1994) (PubMed).
: "Molecular cloning of two isoforms of the plasma membrane Ca2+-transporting ATPase from rat brain. Structural and functional domains exhibit similarity to Na+,K+- and other cation transport ATPases." in: The Journal of biological chemistry, Vol. 263, Issue 18, pp. 8646-57, (1988) (PubMed).
Synonyms and alternative names related to ATP2B2
ATPase plasma membrane Ca2+ transporting 2 (ATP2B2), ATPase, Ca++ transporting, plasma membrane 2 (Atp2b2), ATPase plasma membrane Ca2+ transporting 2 (Atp2b2), ATPase, Ca++ transporting, plasma membrane 2 (atp2b2), ATPase plasma membrane Ca2+ transporting 2 (atp2b2), ATP2B2, ATP2B4, D6Abb2e, dfw, jog, PMCA, PMCA2, PMCA2a, PMCA2i, Tmy, wms, wriProtein level used designations for ATP2B2
- plasma membrane Ca(2+)-ATPase
- plasma membrane Ca2+ pump 2
- plasma membrane calcium ATPase
- plasma membrane calcium pump
- plasma membrane calcium-transporting ATPase 2
- ATPase, Ca++ transporting, plasma membrane 4
- plasma membrane calcium ATPase 2
- ATPase, Ca++ transporting, plasma membrane 2
- plasma membrane calcium-transporting ATPase 4
- deaf waddler
- wriggle
- ATPase isoform 2 Na+K+ transporting beta polypeptide 2
- ATPase isoform 2, Na+K+ transporting, beta polypeptide 2
- plasma membrane Ca++-ATPase
- pmca2
- plasma membrane calcium-transporting ATPase 2-like
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