ATP2B1 产品
(ATPase, Ca++ Transporting, Plasma Membrane 1 (ATP2B1))
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The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 1. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
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Featured ATP2B1 Categories
Recommended ATP2B1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF, IHC
Validations
- (6)
Cat. No.
ABIN7073155
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Human
Application
WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p), ICC
Validations
- (2)
Cat. No.
ABIN1714863
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN560000
Quantity
100 μg
Datasheet
Datasheet
Recommended ATP2B1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1346041
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our ATP2B1 Products
: "Evidence for a regulated Ca2+ entry in proximal tubular cells and its implication in calcium stone formation." in: Journal of cell science, Vol. 132, Issue 9, (2019) (PubMed).: "Regulation of Intestinal Epithelial Calcium Transport Proteins by Stanniocalcin-1 in Caco2 Cells." in: International journal of molecular sciences, Vol. 17, Issue 7, (2017) (PubMed).
: "UVB irradiation enhances TiO2 nanoparticle-induced disruption of calcium homeostasis in human lens epithelial cells." in: Photochemistry and photobiology, Vol. 90, Issue 6, pp. 1324-31, (2014) (PubMed).
: "UVB irradiation-induced dysregulation of plasma membrane calcium ATPase1 and intracellular calcium homeostasis in human lens epithelial cells." in: Molecular and cellular biochemistry, Vol. 382, Issue 1-2, pp. 263-72, (2013) (PubMed).
: "Insights into the oligomerization process of the C-terminal domain of human plasma membrane Ca²+-ATPase." in: Archives of biochemistry and biophysics, Vol. 506, Issue 2, pp. 194-200, (2011) (PubMed).
: "Sodium accumulation promotes diastolic dysfunction in end-stage heart failure following Serca2 knockout." in: The Journal of physiology, Vol. 588, Issue Pt 3, pp. 465-78, (2010) (PubMed).
: "Maitotoxin converts the plasmalemmal Ca(2+) pump into a Ca(2+)-permeable nonselective cation channel." in: American journal of physiology. Cell physiology, Vol. 297, Issue 6, pp. C1533-43, (2009) (PubMed).
: "Splice-site A choice targets plasma-membrane Ca2+-ATPase isoform 2 to hair bundles." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 23, pp. 6172-80, (2006) (PubMed).
: "Expression of calcium transporters in the retina of the tiger salamander (Ambystoma tigrinum)." in: The Journal of comparative neurology, Vol. 475, Issue 4, pp. 463-80, (2004) (PubMed).
: "Plasma membrane Ca2+ pump in rat brain. Patterns of alternative splices seen by isoform-specific antibodies." in: The Journal of biological chemistry, Vol. 272, Issue 38, pp. 23741-7, (1997) (PubMed).
Synonyms and alternative names related to ATP2B1
ATPase plasma membrane Ca2+ transporting 1 (ATP2B1), ATPase, Ca++ transporting, plasma membrane 1 (Atp2b1), ATPase, Ca++ transporting, plasma membrane 1 (atp2b1), ATPase plasma membrane Ca2+ transporting 1 (Atp2b1), plasma membrane calcium-transporting ATPase 2 (LOC100180580), ATPase, Ca++ transporting, plasma membrane 1a (atp2b1a), ATPase, Ca++ transporting, plasma membrane 1 L homeolog (atp2b1.L), 2810442I22Rik, ATP2B1, atp2b1, atp2b1b, DKFZp459A1127, E130111D10Rik, PMCA, PMCA1, Pmca1, pmca1, Pmca1a, pmca1a, Pmca1b, Pmca1c, PMCA1kb, sb:cb801, si:dkey-18o7.1, wu:fe47b06, wu:fi41d01Protein level used designations for ATP2B1
- plasma membrane calcium pump
- plasma membrane calcium-transporting ATPase 1
- PMCA1
- plasma membrane calcium ATPase
- plasma membrane calcium ATPase 1
- Ca2+/Mg2+ ATPase
- ATPase, Ca++ transporting, plasma membrane 1
- plasma membrane calcium-transporting ATPase 1-like
- plasma membrane Ca2+ pump (PMCA1b)
- ATPase, Ca++ transporting, plasma membrane 1 L homeolog
- fibronectin
- plasma membrane calcium ATPase 1b
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