ATP2A2 抗体
(ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2))
This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2008].
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Popular ATP2A2 抗体
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Cat. No.
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Datasheet
Reactivity
Human
Application
WB, IHC, IF
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Cat. No.
ABIN3021430
Quantity
100 μL
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Datasheet
Reactivity
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Application
WB, IHC, IP, ICC
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- (5)
Cat. No.
ABIN7436261
Quantity
100 μL
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Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (5)
Cat. No.
ABIN3030067
Quantity
100 μg
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Datasheet
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Human
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WB, ELISA, IHC, IF
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- (3)
Cat. No.
ABIN7168600
Quantity
100 μg
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Datasheet
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Human, Mouse, Rat
Application
WB, ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN1686784
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, IHC (p)
Validations
- (1)
- (3)
Cat. No.
ABIN3043793
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p)
Validations
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Cat. No.
ABIN3187946
Quantity
100 μL
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Datasheet
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Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
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Cat. No.
ABIN6260121
Quantity
100 μL
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Datasheet
Reactivity
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Application
WB, IP
Validations
- (2)
Cat. No.
ABIN7265753
Quantity
100 μL
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Datasheet
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Human, Rat
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WB, IHC (p)
Validations
- (1)
- (2)
Cat. No.
ABIN3044280
Quantity
100 μg
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Datasheet
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Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB, IHC
Validations
- (3)
Cat. No.
ABIN2782136
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7185523
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Bat, Chicken, Cow, Dog, Drosophila melanogaster, Guinea Pig, Horse, Human, Insect, Monkey, Mouse, Pig, Rabbit, Rat, Xenopus laevis, Zebrafish (Danio rerio)
Application
WB, IHC, IHC (p)
Validations
- (1)
Cat. No.
ABIN6755314
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Drosophila melanogaster, Human, Mouse, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN634681
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF, ICC
Validations
- (2)
Cat. No.
ABIN7042954
Quantity
50 μL
Datasheet
Datasheet
Latest Publications for our ATP2A2 抗体
: "Iron-deficiency anemia reduces cardiac contraction by downregulating RyR2 channels and suppressing SERCA pump activity." in: JCI insight, Vol. 4, Issue 7, (2019) (PubMed).: "The E3 ubiquitin ligase NEDD4 is an LC3-interactive protein and regulates autophagy." in: Autophagy, Vol. 13, Issue 3, pp. 522-537, (2017) (PubMed).
: "Depressed calcium cycling contributes to lower ischemia tolerance in hearts of estrogen-deficient rats." in: Menopause (New York, N.Y.), Vol. 22, Issue 7, pp. 773-82, (2015) (PubMed).
: "Amyloid beta a4 precursor protein-binding family B member 1 (FE65) interactomics revealed synaptic vesicle glycoprotein 2A (SV2A) and sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) as ..." in: Molecular & cellular proteomics : MCP, Vol. 13, Issue 2, pp. 475-88, (2014) (PubMed).
: "Right ventricular pacing with mechanical dyssynchrony causes apoptosis interruptus and calcium mishandling." in: The Canadian journal of cardiology, Vol. 29, Issue 4, pp. 510-8, (2013) (PubMed).
: "Extramitochondrial domain rich in carbonic anhydrase activity improves myocardial energetics." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 10, pp. E958-67, (2013) (PubMed).
: "Low density lipoproteins promote unstable calcium handling accompanied by reduced SERCA2 and connexin-40 expression in cardiomyocytes." in: PLoS ONE, Vol. 8, Issue 3, pp. e58128, (2013) (PubMed).
: "Extracellular matrix of mechanically stretched cardiac fibroblasts improves viability and metabolic activity of ventricular cells." in: International journal of medical sciences, Vol. 10, Issue 13, pp. 1837-45, (2013) (PubMed).
: "Protein aggregation of SERCA2 mutants associated with Darier disease elicits ER stress and apoptosis in keratinocytes." in: Journal of cell science, Vol. 124, Issue Pt 21, pp. 3568-80, (2011) (PubMed).
: "Long-term effects of epoprostenol on the pulmonary vasculature in idiopathic pulmonary arterial hypertension." in: Chest, Vol. 138, Issue 5, pp. 1234-9, (2010) (PubMed).
Aliases for ATP2A2 抗体
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 S homeolog (atp2a1.S) 抗体ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 (ATP2A2) 抗体
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 (Atp2a2) 抗体
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (Atp2a2) 抗体
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2a (atp2a2a) 抗体
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