ATF4 产品
(Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))
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This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. [provided by RefSeq, Sep 2011].
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Featured ATF4 Categories
ATF4 抗体
High quality antibodies with extensive validation data.
ATF4 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
ATF4 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ATF4 抗体
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Reactivity
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Cat. No.
ABIN7433582
Quantity
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Datasheet
Datasheet
Reactivity
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- (5)
Cat. No.
ABIN559979
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Cat. No.
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Recommended ATF4 ELISA试剂盒
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Cat. No.
ABIN6964570
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Recommended ATF4 蛋白
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ABIN1345933
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Cat. No.
ABIN7121669
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Reactivity
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Latest Publications for our ATF4 Products
: "Fibroblast-enriched endoplasmic reticulum protein TXNDC5 promotes pulmonary fibrosis by augmenting TGFβ signaling through TGFBR1 stabilization." in: Nature communications, Vol. 11, Issue 1, pp. 4254, (2020) (PubMed).: "Cellular stress due to impairment of collagen prolyl hydroxylation complex is rescued by the chaperone 4-phenylbutyrate." in: Disease models & mechanisms, Vol. 12, Issue 6, (2019) (PubMed).
: "EndophilinA2 protects against angiotensin II-induced cardiac hypertrophy by inhibiting angiotensin II type 1 receptor trafficking in neonatal rat cardiomyocytes." in: Journal of cellular biochemistry, (2018) (PubMed).
: "Adipose-specific lipin1 overexpression in mice protects against alcohol-induced liver injury." in: Scientific reports, Vol. 8, Issue 1, pp. 408, (2018) (PubMed).
: "Selenoprotein S silencing triggers mouse hepatoma cells apoptosis and necrosis involving in intracellular calcium imbalance and ROS-mPTP-ATP." in: Biochimica et biophysica acta. General subjects, Vol. 1862, Issue 10, pp. 2113-2123, (2018) (PubMed).
: "Identification of ASB7 as ER stress responsive gene through a genome wide in silico screening for genes with ERSE." in: PLoS ONE, Vol. 13, Issue 4, pp. e0194310, (2018) (PubMed).
: "Activation of the Integrated Stress Response and Metabolic Dysfunction in a Murine Model of Sleep Apnea." in: American journal of respiratory cell and molecular biology, Vol. 57, Issue 4, pp. 477-486, (2017) (PubMed).
: "Downregulation of miR-384-5p attenuates rotenone-induced neurotoxicity in dopaminergic SH-SY5Y cells through inhibiting endoplasmic reticulum stress." in: American journal of physiology. Cell physiology, Vol. 310, Issue 9, pp. C755-63, (2016) (PubMed).
: "HOXB9 acts as a negative regulator of activated human T cells in response to amino acid deficiency." in: Immunology and cell biology, Vol. 94, Issue 6, pp. 612-7, (2016) (PubMed).
: "Glutathione S-Transferase P-Mediated Protein S-Glutathionylation of Resident Endoplasmic Reticulum Proteins Influences Sensitivity to Drug-Induced Unfolded Protein Response." in: Antioxidants & redox signaling, (2016) (PubMed).
Synonyms and alternative names related to ATF4
activating transcription factor 4 (ATF4), activating transcription factor 4 (atf4), activating transcription factor 4 (Atf4), activating transcription factor 4 L homeolog (atf4.L), activating transcription factor 4a (atf4a), activating transcription factor 4b (atf4b), activating transcription factor 4 S homeolog (atf4.S), atf-4, Atf-4, ATF4, atf4, atf4-a, atf4-b, ATF4-I, atf4-ii, C/ATF, CREB-2, creb-2, CREB2, creb2, sb:eu681, TAXREB67, taxreb67, TXREB, txreb, wu:fb08f07, wu:fj01c08, wu:fk30b04, zgc:85951, zgc:171702Protein level used designations for ATF4
- DNA-binding protein TAXREB67
- cAMP response element-binding protein 2
- cAMP-dependent transcription factor ATF-4
- cAMP-responsive element-binding protein 2
- cyclic AMP-dependent transcription factor ATF-4
- cyclic AMP-responsive element-binding protein 2
- tax-responsive enhancer element B67
- tax-responsive enhancer element-binding protein 67
- activating transcription factor 4 (tax-responsive enhancer element B67)
- activating transcription factor ATF-4
- rATF-4
- activating transcription factor 4
- c/EBP-related ATF
- tax-responsive enhancer element-binding protein 67 homolog
- taxREB67 homolog
- Activating Transcription Factor 4 -I
- Activating Transcription Factor 4 -II
- activating transcription factor 4 S homeolog
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