Ataxin 3 产品
(Ataxin 3 (ATXN3))
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Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Sep 2009].
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Ataxin 3 抗体
High quality antibodies with extensive validation data.
Ataxin 3 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Ataxin 3 抗体
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Cat. No.
ABIN3021829
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
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- (3)
Cat. No.
ABIN2856981
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Cat. No.
ABIN7144793
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Recommended Ataxin 3 ELISA试剂盒
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ABIN418941
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ABIN6201829
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Recommended Ataxin 3 蛋白
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ABIN1346195
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10 μg
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Cat. No.
ABIN1346197
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Reactivity
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Source
Escherichia coli (E. coli)
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ABIN935045
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Latest Publications for our Ataxin 3 Products
: "The Truncated C-terminal Fragment of Mutant ATXN3 Disrupts Mitochondria Dynamics in Spinocerebellar Ataxia Type 3 Models." in: Frontiers in molecular neuroscience, Vol. 10, pp. 196, (2017) (PubMed).: "Ataxin-3 expression correlates with the clinicopathologic features of gastric cancer." in: International journal of clinical and experimental medicine, Vol. 7, Issue 4, pp. 973-81, (2014) (PubMed).
: "Molecular architecture of CAG repeats in human disease related transcripts." in: Journal of molecular biology, Vol. 340, Issue 4, pp. 665-79, (2004) (PubMed).
: "Sequence-dependent and independent inhibition specific for mutant ataxin-3 by small interfering RNA." in: Annals of neurology, Vol. 56, Issue 1, pp. 124-9, (2004) (PubMed).
: "Structural and functional analysis of ataxin-2 and ataxin-3." in: European journal of biochemistry / FEBS, Vol. 271, Issue 15, pp. 3155-70, (2004) (PubMed).
: "The C-type lectin domains of lecticans, a family of aggregating chondroitin sulfate proteoglycans, bind tenascin-R by protein-protein interactions independent of carbohydrate moiety." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 19, pp. 10116-21, (1997) (PubMed).
: "Machado-Joseph disease gene product is a cytoplasmic protein widely expressed in brain." in: Annals of neurology, Vol. 41, Issue 4, pp. 453-62, (1997) (PubMed).
Synonyms and alternative names related to Ataxin 3
ataxin 3 (atxn3), ataxin 3 (ATXN3), ataxin 3 L homeolog (atxn3.L), ataxin-3 (MICPUN_104046), ataxin-3 (MICPUCDRAFT_46658), ataxin 3 (Atxn3), 2210008M02Rik, AI463012, AI647473, at3, AT3, ataxin-3, atx3, ATX3, ATXN3, jos, JOS, MGC83584, Mjd, mjd, MJD, mjd1, MJD1, Rsca3, sca3, SCA3, Sca3, zgc:56323Protein level used designations for Ataxin 3
- ataxin-3
- ataxin 3
- ataxin-3-like
- Machado-Joseph disease (spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, autosomal dominant, ataxin 3)
- Machado-Joseph disease protein 1
- ataxin 3 variant h
- ataxin 3 variant m
- ataxin 3 variant ref
- josephin
- olivopontocerebellar ataxia 3
- spinocerebellar ataxia type 3 protein
- Machado-Joseph disease (spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, autosomal dominant, ataxin 3) homolog
- machado-Joseph disease protein 1 homolog
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