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Ataxin 2 抗体

(Ataxin 2 (ATXN2))

The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. Defects in this gene are the cause of spinocerebellar ataxia type 2 (SCA2). SCA2 belongs to the autosomal dominant cerebellar ataxias type I (ADCA I) which are characterized by cerebellar ataxia in combination with additional clinical features like optic atrophy, ophthalmoplegia, bulbar and extrapyramidal signs, peripheral neuropathy and dementia. SCA2 is caused by expansion of a CAG repeat in the coding region of this gene. This locus has been mapped to chromosome 12, and it has been determined that the diseased allele contains 37-50 CAG repeats, compared to 17-29 in the normal allele. Longer expansions result in earlier onset of the disease. Alternatively spliced transcript variants encoding different isoforms have been identified but their full length sequence has not been determined. [provided by RefSeq, Jan 2010].

recommended

Ataxin 2 抗体 (ABIN7259314)

ATXN2 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

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recommended

Ataxin 2 抗体 (C-Term) (ABIN3028477)

ATXN2 适用: 人, 小鼠, 大鼠 WB, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated

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recommended

Ataxin 2 抗体 (AA 775-856) (ABIN872411)

ATXN2 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

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Find Ataxin 2 抗体 for a variety of species such as anti-Human Ataxin 2, anti-Mouse Ataxin 2, anti-Rat Ataxin 2. The species listed below are among those available. Click on a link to go to the corresponding products.

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Popular Ataxin 2 抗体

Product

Reactivity

Application

Validations

Cat. No.

Quantity

Datasheet

anti-Ataxin 2 抗体

Reactivity Human, Mouse, Rat

Application IHC, IF

Validations

Cat. No. ABIN7259314

Quantity 200 μL

Datasheet Datasheet

anti-Ataxin 2 抗体 (C-Term)

Reactivity Human, Mouse, Rat

Application WB, IF, ICC, FACS

Validations

Cat. No. ABIN3028477

Quantity 100 μg

Datasheet Datasheet

anti-Ataxin 2 抗体 (AA 775-856)

Reactivity Mouse

Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)

Validations

Cat. No. ABIN872411

Quantity 100 μL

Datasheet Datasheet

anti-Ataxin 2 抗体 (Internal Region)

Reactivity Human

Application ELISA, IF, FACS

Validations

Cat. No. ABIN570879

Quantity 100 μg

Datasheet Datasheet

anti-Ataxin 2 抗体 (C-Term)

Reactivity Human, Mouse, Rat

Application WB, IHC (p)

Validations

Cat. No. ABIN3043507

Quantity 100 μg

Datasheet Datasheet

anti-Ataxin 2 抗体 (AA 174-383)

Reactivity Human

Application WB, ELISA, IF

Validations

Cat. No. ABIN7144789

Quantity 100 μg

Datasheet Datasheet

anti-Ataxin 2 抗体 (Internal Region)

Reactivity Human

Application WB, ELISA, IF, ICC

Validations

Cat. No. ABIN6256953

Quantity 100 μL

Datasheet Datasheet

anti-Ataxin 2 抗体 (AA 725-757)

Reactivity Human

Application WB

Validations

Cat. No. ABIN6242193

Quantity 200 μL

Datasheet Datasheet

anti-Ataxin 2 抗体 (AA 321-355)

Reactivity Human, Mouse

Application WB

Validations

Cat. No. ABIN6242194

Quantity 200 μL

Datasheet Datasheet

anti-Ataxin 2 抗体 (AA 1214-1313)

Reactivity Human

Application WB, ELISA

Validations

Cat. No. ABIN562798

Quantity 50 μL

Datasheet Datasheet

anti-Ataxin 2 抗体 (Middle Region)

Reactivity Cow, Dog, Human, Mouse

Application WB

Validations

Cat. No. ABIN927703

Quantity 100 μL

Datasheet Datasheet

anti-Ataxin 2 抗体 (Middle Region)

Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat

Application WB, IHC

Validations

Cat. No. ABIN2780458

Quantity 100 μL

Datasheet Datasheet

anti-Ataxin 2 抗体 (AA 775-856) (Biotin)

Reactivity Mouse

Application WB, ELISA, IHC (p), IHC (fro)

Validations

Cat. No. ABIN884130

Quantity 100 μL

Datasheet Datasheet

anti-Ataxin 2 抗体 (AA 775-856) (AbBy Fluor® 750)

Reactivity Mouse

Application WB, IF (cc), IF (p)

Validations

Cat. No. ABIN4997063

Quantity 100 μL

Datasheet Datasheet

anti-Ataxin 2 抗体 (AA 775-856) (AbBy Fluor® 647)

Reactivity Mouse

Application WB, IF (cc), IF (p)

Validations

Cat. No. ABIN884129

Quantity 100 μL

Datasheet Datasheet

Latest Publications for our Ataxin 2 抗体

Abraham, Chan, Salvi, Ho, Hall, Vidya, Guo, Killackey, Liu, Lee, Brown, Mekhail: "Intersection of calorie restriction and magnesium in the suppression of genome-destabilizing RNA-DNA hybrids." in: Nucleic acids research, Vol. 44, Issue 18, pp. 8870-8884, (2016) (PubMed).

Xia, Santostefano, Hamazaki, Liu, Subramony, Terada, Ashizawa: "Generation of human-induced pluripotent stem cells to model spinocerebellar ataxia type 2 in vitro." in: Journal of molecular neuroscience : MN, Vol. 51, Issue 2, pp. 237-48, (2013) (PubMed).

Kaehler, Isensee, Nonhoff, Terrey, Hucho, Lehrach, Krobitsch: "Ataxin-2-like is a regulator of stress granules and processing bodies." in: PLoS ONE, Vol. 7, Issue 11, pp. e50134, (2012) (PubMed).

Dubois, Trynka, Franke, Hunt, Romanos, Curtotti, Zhernakova, Heap, Adány, Aromaa, Bardella, van den Berg, Bockett, de la Concha, Dema, Fehrmann, Fernández-Arquero, Fiatal, Grandone, Green, Groen et al.: "Multiple common variants for celiac disease influencing immune gene expression. ..." in: Nature genetics, Vol. 42, Issue 4, pp. 295-302, (2010) (PubMed).

Huynh, Del Bigio, Ho, Pulst: "Expression of ataxin-2 in brains from normal individuals and patients with Alzheimer's disease and spinocerebellar ataxia 2." in: Annals of neurology, Vol. 45, Issue 2, pp. 232-41, (1999) (PubMed).

Nechiporuk, Huynh, Figueroa, Sahba, Nechiporuk, Pulst: "The mouse SCA2 gene: cDNA sequence, alternative splicing and protein expression." in: Human molecular genetics, Vol. 7, Issue 8, pp. 1301-9, (1998) (PubMed).

Pulst, Nechiporuk, Nechiporuk, Gispert, Chen, Lopes-Cendes, Pearlman, Starkman, Orozco-Diaz, Lunkes, DeJong, Rouleau, Auburger, Korenberg, Figueroa, Sahba: "Moderate expansion of a normally biallelic trinucleotide repeat in spinocerebellar ataxia type 2." in: Nature genetics, Vol. 14, Issue 3, pp. 269-76, (1996) (PubMed).

Aliases for Ataxin 2 抗体

ataxin 2 (ATXN2) 抗体
ataxin 2 (Atxn2) 抗体
ataxin 2 L homeolog (atxn2.L) 抗体
9630045M23Rik 抗体
ASL13 抗体
ATX2 抗体
ATXN2 抗体
AW544490 抗体
MGC115230 抗体
SCA2 抗体
Sca2 抗体
TNRC13 抗体

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