电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Ataxin 1 蛋白

(Ataxin 1 (ATXN1))
The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. The function of the ataxins is not known. This locus has been mapped to chromosome 6, and it has been determined that the diseased allele contains 41-81 CAG repeats, compared to 6-39 in the normal allele, and is associated with spinocerebellar ataxia type 1 (SCA1). At least two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2010].
Ataxin 1 Protein (ATXN1) (AA 576-675) (GST tag) Ataxin 1 Protein (ATXN1) (AA 576-675) (GST tag) Ataxin 1 Protein (ATXN1) (AA 576-675) (GST tag) (ABIN1346189)

ATXN1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

Ataxin 1 Protein (ATXN1) (AA 569-807) (His tag) (ABIN7390679)

ATXN1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, Imm, PC

Ataxin 1 Protein (ATXN1) (AA 331-587) (His tag) (ABIN7415551)

ATXN1 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, Imm, PC

Ataxin 1 蛋白 by Origin

Find Ataxin 1 蛋白 for a variety of species such as anti-Human Ataxin 1, anti-Mouse Ataxin 1. The species listed below are among those available. Click on a link to go to the corresponding products.

Ataxin 1 蛋白 by Source

Here you will find Ataxin 1 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Ataxin 1 蛋白 by 蛋白类型

Here you can find Ataxin 1 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

Ataxin 1 蛋白 by 应用范围

Find Ataxin 1 蛋白 validated for a specific application such as WB, SDS, ELISA, AbP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Ataxin 1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1346189
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7390679
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7415551
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3089722
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3119805
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2715013
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2715012
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our Ataxin 1 蛋白

Yoon, Abdelmohsen, Kim, Yang, Martindale, Tominaga-Yamanaka, White, Orjalo, Rinn, Kreft, Wilson, Gorospe: "Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination." in: Nature communications, Vol. 4, pp. 2939, (2013) (PubMed).

Aliases for Ataxin 1 蛋白

ataxin 1 (ATXN1) 蛋白
ataxin 1b (atxn1b) 蛋白
ataxin 1 (Atxn1) 蛋白
Ataxin 1 (Atx-1) 蛋白
2900016G23Rik 蛋白
ataxin 1b 蛋白
ATX1 蛋白
Atx1 蛋白
ATXN1 蛋白
atxn1 蛋白
C85907 蛋白
CG4547 蛋白
D6S504E 蛋白
dAtx-1 蛋白
dAtx1 蛋白
Dmel\\CG4547 蛋白
ENSMUSG00000074917 蛋白
Gm10786 蛋白
SCA1 蛋白
Sca1 蛋白
sca1 蛋白
You are here:
客服