The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
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Anasa, Manickam, Talwar, Ravanan: "Identification of ASB7 as ER stress responsive gene through a genome wide in silico screening for genes with ERSE." in: PLoS ONE, Vol. 13, Issue 4, pp. e0194310, (2018) (PubMed).
Synonyms and alternative names related to ASB7
ankyrin repeat and SOCS box containing 7 (ASB7), ankyrin repeat and SOCS box-containing 7 (Asb7), ankyrin repeat and SOCS box containing 7 L homeolog (asb7.L), ankyrin repeat and SOCS box containing 7 (Asb7), ankyrin repeat and SOCS box containing 7 (asb7), AI449039, Asb-7, ASB-7, asb7, D030055C23Rik, zgc:77381
Protein level used designations for ASB7
ankyrin repeat and SOCS box protein 7
ankyrin repeat and SOCS box-containing 7
ankyrin repeat and SOCS box-containing protein 7
ASB-7
ankyrin repeat and SOCS box containing 7 L homeolog