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ASAH2 产品

(N-Acylsphingosine Amidohydrolase (Non-Lysosomal Ceramidase) 2 (ASAH2))
Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816]).[supplied by OMIM, Mar 2008].

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Featured ASAH2 Categories

ASAH2 抗体

High quality antibodies with extensive validation data.

ASAH2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

ASAH2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ASAH2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7161486
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (3)
Cat. No. ABIN7264037
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN604683
Quantity 0.05 mg
Datasheet Datasheet

Recommended ASAH2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958013
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6730406
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6385374
Quantity 96 tests
Datasheet Datasheet

Recommended ASAH2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7197085
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7415830
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN6124928
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our ASAH2 Products

Osawa, Uchinami, Bielawski, Schwabe, Hannun, Brenner: "Roles for C16-ceramide and sphingosine 1-phosphate in regulating hepatocyte apoptosis in response to tumor necrosis factor-alpha." in: The Journal of biological chemistry, Vol. 280, Issue 30, pp. 27879-87, (2005) (PubMed).

Tani, Iida, Ito: "O-glycosylation of mucin-like domain retains the neutral ceramidase on the plasma membranes as a type II integral membrane protein." in: The Journal of biological chemistry, Vol. 278, Issue 12, pp. 10523-30, (2003) (PubMed).

Nilsson, Duan: "Alkaline sphingomyelinases and ceramidases of the gastrointestinal tract." in: Chemistry and physics of lipids, Vol. 102, Issue 1-2, pp. 97-105, (2000) (PubMed).

Synonyms and alternative names related to ASAH2

N-acylsphingosine amidohydrolase 2 (ASAH2), N-acylsphingosine amidohydrolase 2 (Asah2), AI585898, BCDase, HNAC1, LCDase, N-CDase, NCDase

Protein level used designations for ASAH2

  • N-acylsphingosine amidohydrolase 2
  • acylsphingosine deacylase 2
  • mitochondrial ceramidase
  • neutral ceramidase
  • neutral/alkaline ceramidase
  • non-lysosomal ceramidase
  • N-CDase
  • NCDase
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