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Myeloid-Derived Suppressor Cell Markers

Myeloid-Derived Suppressor Cells (MDSCs) cells are a heterogeneous population of immature myeloid cells that play a critical role in dampening immune responses and promoting immune evasion by tumors. They have gained significant attention in both research and diagnostic contexts for their unique immunosuppressive properties.

In diagnostics, monitoring MDSC levels in patients with cancer and other diseases can provide insights into the immune status and potential for immune evasion. Elevated MDSC counts are often associated with a compromised immune response and can inform treatment decisions. In research, MDSCs are the focus of intense study to understand their mechanisms of immunosuppression and their roles in various diseases, particularly cancer. Researchers investigate ways to target MDSCs as a potential strategy to enhance anti-tumor immune responses.

The study of MDSCs is a rapidly evolving field, with implications for both cancer immunotherapy and our understanding of immune regulation in various disease contexts. Investigating MDSC biology holds promise for the development of novel diagnostic markers and therapeutic strategies to modulate immune responses effectively. An example of an antibody marker for MDSCs is CD11b, which can be used to identify and quantify MDSCs in experimental settings. For instance, in a research study on cancer immunotherapy, CD11b antibodies might be employed to track the presence and abundance of MDSCs in tumor microenvironments. High levels of MDSCs may indicate a more immunosuppressive environment, influencing treatment strategies. High levels of MDSCs may indicate a more immunosuppressive environment, influencing treatment strategies. antibodies-online offers a set of antibodies, tailored to target key markers on MDSCs . Browse the table below to find your suitable marker.

Myeloid-Derived Suppressor Cell Markers Antibodies

Product
Reactivity
Clone
Application
Validations
Cat. No.
Quantity
Reactivity Human, Mouse, Rabbit, Rat
Clone
Application WB, FACS, ELISA, IHC (p), IHC (fro), ICC, IF (p), IF (cc)
Validations
  • (16)
  • (6)
Cat. No. ABIN670806
Quantity 100 μL
Reactivity Human, Mouse, Rabbit, Rat
Clone
Application WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro)
Validations
  • (1)
  • (7)
Cat. No. ABIN703706
Quantity 100 μL
Reactivity Human, Mouse, Rat
Clone
Application FACS
Validations
  • (4)
  • (7)
Cat. No. ABIN741285
Quantity 100 μL
Reactivity Human
Clone
Application WB, IHC, ELISA, FACS, IF
Validations
  • (7)
Cat. No. ABIN335161
Quantity 100 μg
Reactivity Human
Clone
Application WB, IHC, IF
Validations
  • (7)
Cat. No. ABIN7270129
Quantity 100 μL
Reactivity Human, Mouse, Rat
Clone
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN7259098
Quantity 200 μL
Reactivity Human
Clone 1G3D7
Application FACS, ELISA, IHC
Validations
  • (4)
Cat. No. ABIN7193387
Quantity 100 μL
Reactivity Human
Clone
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7158547
Quantity 100 μg
Reactivity Human, Mouse
Clone
Application WB, IHC, IF
Validations
  • (3)
Cat. No. ABIN7257038
Quantity 200 μL
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